EXPERT OPINION approach is introduced . First of all , in oncology , when dealing with a particular oncological disease , doctors look for a specific drug or treatment method , to which the tumor is most sensitive .
We can see the same in reproductive medicine . This variety of methods and pharmacological tools give us opportunities to choose a specific treatment method for each patient .
There is no limit to perfection in personification . I believe that soon we will determine the genotype characteristics of patients with different forms of infertility , a certain polymorphism of genes – this is a future . But today there is an opportunity to personalize our approaches . First , we work with each patient individually . Depending on his / her status and reasons of infertility , we determine a treatment method , and drugs are selected considering a large number of factors . The specific patient ’ s protocol is taken into account and selected ; the stimulation schemes are maximally personalized . The most personalized method is the opportunity to use the gene diagnostics . Despite the fact that we operate only once year , the ‘ Persona ’ was the first in Kazakhstan to open a laboratory able to determine all 46 chromosomes in an embryo prior to transfer . Pre-implantation diagnosis existed in Kazakhstan already , but we have implemented the ICGH method that allows the determination of all 24 pairs of chromosomes . We transfer a proven healthy embryo and guarantee 99 percent lack of chromosomal pathology . This increased effectiveness by up to 50- 70-80 percent for patients who have had a history of failed IVF , especially for older women , in cases when the pregnancy did not occur previously . Some patients cannot undergo a transfer , because all embryos are changed , especially for women after 40 years of age .
This method , in my opinion , is the height of that personified approach , which is possible in reproductive medicine . In the future , we will be able to identify monogenic diseases . Then , we will be able to say with 100 percent probability that we transfer a healthy embryo . It will be possible to avoid many diseases that are not diagnosed today during pregnancy , to give to the opportunity for a child to be born healthy .
Speaking about genetics in Kazakhstan and new opportunities of IVF , how do you assess the problem of infertility in Kazakhstan ? This problem concerns me , as I am a specialist in fertility treatment and president of the Kazakhstan ’ s Association of Reproductive Medicine .
In Kazakhstan , like all over the world , the infertility occurrence is about 15 percent , there is no downward trend . Moreover , we see that the number of fertility-challenged couples is even increasing . When we say that in Kazakhstan about 150-160 thousands of marriages are effected every year , and 20 thousand patients among them have problems with the birth of children . And this army is being replenished all the time . Today , there are about seven thousand programs of in-vitro fertilization in Kazakhstan , and approximately 400-420 programs per million people is absolutely not enough . If we look at European countries , the standard there is one thousand programs per one million people . This suggests that many people today cannot attend a doctor because for financial reasons , lack of knowledge , or useless doctor methods . This is why the reproductive medicine in Kazakhstan possesses great potential . Approximately 40 percent of couples need a supportive treatment by means of reproductive technologies .
Speaking about the couples having problems with the birth of children : how do they understand that they need to consult a reproductive health professional ? If the spouse , in particular a woman under 45 years of age , maintains a normal sex life without using any protection and there is no pregnancy within one year , it means that we can diagnose infertility . The spouses after 38 must come to a doctor even earlier . If you notice that pregnancy does not occur in six months , you can contact a reproductive health professional to find the causes of infertility .
What is the situation with quotas in Kazakhstan , including your center ? Since the 2000s , by our initiative , the Ministry of Health has begun supporting patients with infertility . In 2010 , 250 quotas have been given . Now their number has increased to almost 900 quotas in this year . From the next year we plan to work in the insurance system , and I believe that due to this the number of quotas will increase further . Currently about five clinics that have been established long ago provide treatment by quotas .
How is the situation with donation in Kazakhstan ? The situation with sperm donorship is not good , as there are not so many willing to be donors . The requirements are not so complicated : a man should already have a child and be under 35 . It ’ s important to be healthy genetically , physically and in appearance , with above-average education , preferably higher education . Despite the fact that we call for donors , this problem of a shortage still exists .
The situation with oocyte donors is better . Maybe , such donors are paid better for delivery of oocytes . We have a donor egg bank , which we can use for
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