Vet360 Vol 4 Issue 3 June 2017 Vet360 - Page 9

INFECTIOUS DISEASES The clinical course of the disease in dogs is extremely rapid and resembles the peracute pulmonary form observed in horses. Figure 1: Diffuse interstitial pneumonia, serofibrinous pleuritis and ventral atelectasis indicative of fluid accumulation. Post mortem examination typically reveals moderate serofibrinous pleuritis, severe interstitial pneumonia, severe mediastinal oedema and moderate visceral congestion. Histologically, the lungs show the most diagnostic lesions which are characterised by a protein-rich alveolar and interstitial oedema, mono- nuclear leukocytic interstitial pneumonia and multi- focal haemorrhage. cAHS was confirmed by positive AHS-specific immunohistochemical labelling in all cases and real-time PCR in most of the cases. of African horsesickness virus from naturally infected dogs in Upper Egypt." Canadian Journal of Compar- ative Medicine 45(4): 392. 5. Theiler, A. (1906). "Transmission of horse sickness into dogs." Rep. Govern. Vet. Bacteriol: 160-162. 6. Van Rensberg, I., et al. (1981). "An outbreak of African horsesickness in dogs." Journal of the South African Veterinary Association 52(4): 323-325. In clinical cases of ARDS, cAHS should be included as a differential diagnosis and EDTA-blood can be sub- mitted for rPCR confirmation to the Equine Research Centre at the Onderstepoort Genetics Laboratory. At necropsy collection of a full set of organs (esp. lungs) in 10% buffered formalin for histopathology and im- munohistochemistry as well as fresh lung and spleen on ice for rPCR will assist in confirmation of cAHS. Although the exact mode of transmission has not been confirmed, it is suspected to be vector borne, therefore owners should be advised to implement tick & fly/midge control in high risk areas during late sum- mer and autumn. Once clinical signs appear, a very high mortality rate (estimated to be >90%) can be ex- pected in spite of veterinary intervention. REFERENCES: 1. Braverman, Y. and A. Chizov-Ginzburg (1996). "Role of dogs (Canis domesticus) as hosts for African horse sickness virus." Veterinary microbiology 51(1): 19-25. 2. Howell, P. (1963). "Emerging diseases of animals. II. African horsesickness, FAO Agric." Stud 61: 71-108. 3. Piercy, S. (1951). "Some observations on African horse-sickness including an account of an outbreak among dogs, East Afr." Agric. J 17: 62-64. 4. Salama, S., et al. (1981). "Isolation and identification Advanced Course in Wildlife Chemical Immobilisation and Field Practice 20–24 November 2017 • • • • Enhance your skills and knowledge in wildlife veterinary practice. Sessions presented in the heart of the Kruger National Park. Partake in a unique solution-based learning experience. Presented by experienced practitioners in wildlife conservation, medicine, pharmacology and research. Contact us today for more information or to book your space. Client Information Centre Tel: +27 (0)12 434 2500 | info@enterprises.up.ac.za SMS the keyword ENTERPRISES followed by VET360 WILDLIFE your name and email to 43366 to receive more information about our full offering. Shifting knowledge to insight enterprises.up.ac.za /vet-science-courses Issue 03 | JUNE 2017 | 9