Vet360 Vol 4 Issue 2 April 2017 Vet360 | Page 33

NUTRITION Nutrition Dr Liesel van der Merwe, BVSc MMedVet(Med)Small Animals University Of Pretoria , Department of Companion animal Clinical Studies Email: [email protected] The Utility of Omega-3 and Omega-6 Fatty Acids in Canine Diets Fat has numerous functions within the body. In the diet, it provides the most concentrated form of energy of all nutrients, providing double the gross energy of protein or carbohydrate. Dietary fat also acts as a carrier that allows the absorption of fat-soluble vitamins and provides essential fatty acids (EFAs) that the body has a physiological requirement for. It’s found in evening primrose, safflower, hemp and borage oils. • AA (arachidonic acid) – AA is found only in animal fats, as well as some fish. Although the dog is able to synthesize adequate amounts of AA during all life stages, its is a conditionally essential nutrient for cats during pregnancy and neonatal development. There are three distinct families of unsaturated fatty acids: Omega-3, Omega-6, and Omega-9. All of them are pol- yunsaturated (PUFAs), having 2 or more double bonds and are named for where in the chain the double bond is made. The different length, number, and type of double bonds dictate different structure and function in the body. The Omega families cannot metabolically interconvert. Sources of Omega 3 PUFAs • α-LA (α-linoleic acid) is considered required as a precursor to the long –chain PUFAs, EPA and DHA, although ex- act requirement levels are not well defined for dogs and cats. It is found in green vegetables, grasses, fruits and plankton, and in flaxseed oil. • EPA (eicosapentaenoic acid) and DHA (docosapentaenoic acid) are long-chain Omega-3 fatty acids that are found in the oils of cold water fish, algae, and to a lesser degree, in the fat of grass-fed land animals. The type of fatty acids in the diet can have significant effects on general health and condition, on immune function and production of inflammatory mediators. Numerous studies and clinical investigations into fatty acid nutrients have concluded that long-chain Omega-3 fats, most notably EPA and DHA, provide important health benefits in humans and domestic animals, including dogs. However, most commercial canine diets contain predominantly Omega-6 (LA, γ-LA, AA) fatty acids. Blood plasma levels of dogs fed these diets usually contain a lower level of omega-3, which can be increased by a dietary change or supplementation. Sources of Omega 6 PUFAs • LA (linoleic acid) is regarded as the most important Ome- ga-6 fatty acid. Deficiencies can cause skin lesions and retarded growth. LA is found in most vegetable oils such as corn, soy, sunflower, as well as chicken and pork fat. • GLA (γ-linoleic acid) – In most animals, including dogs, gamma-linolenic acid (GLA) can be synthesized from LA. PUFAs’ fulfill several main functions: • EPA and DHA support normal cell membrane fluidity giving structural integrity • AA, GLA, EPA, DHA are precursors to the synthesis of eicosanoids, immunoregulatory molecules. • LA is responsible for maintaining the cutaneous water permeability barrier • Cholesterol metabolism and transport (Es kimo people don’t have heart disease!) • AA and DHA Normal retinal and neurological development in neonates AA is precursor of hormonelike group of compounds: prostacyclins, prostaglandins, leukotrienes, and thromboxanes that are involved in processes such as vasodilation, vasoconstriction, muscle contraction, blood pressure Issue 02 | APRIL 2017 | 33