Vet360 Vet360 Vol 06 Issue 02 | Page 26

DERMATOLOGY included in the list of likely allergens. What would we feed in a food trial and why? Hydrolysed protein diets are currently the best way to investigate the role of a dietary allergen in pruritic skin disease. The quality of the hydrolysed diet is very important The more completely hydrolysed the protein source, the better the quality of the trial will be. The quality of the diet is crucial as contamination of the prepared food during production has been shown to compromise the diet. It has also been shown in some cases that the label claim on the food bag does not always match the protein source of the diet in the bag. These factors must weigh on the clinician’s choice of a diet – the higher the quality of the diet used, the more likely the outcome of a trial are to be trustworthy. For how long do we feed the test diet? 80% of dogs with food allergies can be diagnosed with a 5 week trial. Six weeks are necessary to catch the same proportion of cats. By 8 weeks, around 90% of dogs and cats that are food allergic will show a response. For this reason we traditionally conduct trials for 8 weeks. What advice do we give to owners about con- ducting a food trial? Satisfying dermatology practice depends very heavily on excellent communication with the client. Frustration with helping owners with itchy pets can very often be attributed to poor communication, a hurried consultation with inadequate information provided to the owner to give them the opportunity to come on board for what is going to require great compliance over a long time and will invariable cost more than what they were bargaining. A poorly conducted food trial is a huge waste of money time and the owners energy. Here is a suggested discussion framework to use when trying to help pet owners understand how a food trail should be done: 1. Redefine the owner’s definition of ‘success’. To them success invariable means, ‘I fed this diet and the skin got better’. That is not my definition of a successful food trial. Success to us is, ‘I fed this diet in such a way as to be sure that after the completion of the trial, the response I see in the skin (improved or not), is believable’. A well conducted trial provides results that can be trusted – not a particular result. 2. Always help owners decide if a food trial is even doable in their home environments. A dog that comes from a large farm with 10 other dogs that are all fed together may never allow a proper trial. 3. Help owners decide of they will feed all the dogs in the home the prescribed diet or will they feed the affected dog in isolation. Remember, even vet360 Issue 02 | MAY 2019 | 26 4. 5. 6. 7. 8. 9. 10. 11. licking the empty food bowls of other dogs negates the food trial. If there are cats in the environment, their food must be well out of reach of the dog on trial. ALL treats must STOP. Here it important to explore what owners do to treat their dogs and they may not appreciate what you mean by ‘treats’ (biscuits, biltong or droëwors when watch the Saturday game on TV, a bit of fat from the Sunday afternoon braai, to small piece of cheese at bedtime etc) All flavoured medication must be stopped for the trial duration. The only medications that should be allowed are those used to treat serious medical disease (such as drugs used for heart failure or seizure control). Avoid starting a trial over Christmas or other times of the year when there is a lot of food around a family home. Avoid starting a trial that will span a holiday season for the owners. The pets owners must be the ones fully invested in the trial; you cannot expect a sitter to conduct this. Dogs love small children because they leave a trail of half eaten hotdogs, popcorn and chips that they delight in vacuuming up. This destroys a trial. Kids parties are the worst! Anyone who lives or works on the property (in a flatlet, house or garden help) must be fully informed and on board with what is happening. Some dogs love to lick the dirty dishes in the open dishwasher. This is a no-no. Care should be taken to prevent access to food thrown away in the bin or on a compost heap. After this discussion, owners usually understand the seriousness of the trial and that a well conducted trial will almost always result in some level of domestic upheaval. Because many of these pets are really pruritic when we start the diet trial, I will almost always provide some form of oral and/or topical treatment to make their lives more comfortable for the first 6 weeks of the diet trial. The last 2 weeks must be free of all drug use (except shampoo treatment) so that the effect of the diet alone can be unmasked and assessed. I will commonly use oral prednisone or prednisolone at a low dose to at least provide some relief. Oclacitinib (Apoquel®, Zoetis) can also be used very effectively for this purpose. How do we judge response? Assessing response to the diet trial on a daily basis is important. I use a 10-point scale with 0 being a normal dog and 10 being the score that would be given for the worst the owners have ever seen the skin. It is unimportant to me exactly what a 3 or a 7 may mean – what is more important to me is the trend of these scores over time. Owners will have a way of judging the seriousness of the skin disease in their own heads and trying to teach them to adapt this to a strict set of