Vet360 Issue 4 Volume 2 | Page 8

CANINE MEDICINE tone allows bacteria to more easily ascend to the bladder. Abnormal vulvar anatomy and USMI resulted in a moist perivulvar dermatitis and increased the number of pathogenic bacteria at the vulvar opening. Excessive perivulvar skinfolds likely occurred secondary to weight gain. Treatment Georgia was treated with amoxicillin–clavulanic acid at 13.75 mg/kg PO q12h for 4 weeks, indefinite administration of phenylpropanolamine at 1.5 mg/kg PO q12h for sphincter incompetence, local treatment (astringents, hot-packing, topical antibiotics), and an Elizabethan collar to prevent licking of the perivulvar dermatitis. Follow-up The owner reported that the vulva appeared improved and the patient rarely leaked urine and showed none of the previous signs of lower urinary tract inflammation. Urine sediment was inactive. Urine culture 10 days after antibiotic withdrawal showed no growth. Approximately two months after antibiotic treatment was discontinued, Georgia again showed signs of lower urinary tract inflammation (ie, pollakiuria, breaking house training). Urine culture obtained by cystocentesis again yielded E coli but with a markedly different sensitivity profile (sensitive to fluoroquinolones) ? ASK YOURSELF? Is this recurrent urinary tract infection a relapse or re-infection? CORRECT ANSWER Re-infection Recurrent UTIs Relapses are infections caused by the same species of bacteria, usually within several days of treatment cessation. With a relapsed UTI, previous antibacterial treatment failed to eliminate infection. Relapses may be caused by improper antibio ѥ