Vet Lines MSDS PANORAMIS CHEWABLE TABLETS FOR DOGS | Page 6

Repeated dose toxicity
• Spinosad :
Carcinogenicity
• Spinosad :
Reproductive toxicity
• Spinosad :
Mutagenicity
• Spinosad :
Toxicity to fish
• Spinosad
Toxicity to algae
• Spinosad
Toxicity to daphnia
• Spinosad
Biodegradability
• Spinosad
In animals , has been shown to cause vacuolation of cells in liver , kidney , and bone tissues and changes in blood and serum biochemistry . Dose levels producing these effects were many times higher than any dose levels expected from exposure due to use .
Animal testing did not show any carcinogenic effects .
In laboratory animal studies , effects on reproduction have been seen only at doses that produced significant toxicity to the parent animals .
Result in genetic toxicity assays ( in vitro and in vivo ): Negative .
Section 12 - Ecological Information
LC50 / 96 h / Lepomis macrochirus : 5.94 mg / l LC50 / 96 h / Oncorhynchus mykiss : 30 mg / l
EC50 / Pseudokirchneriella subcapitata : > 105.5 ppm EC50 / Navicula sp .: 0.107 mg / l
EC50 / 48 h / Daphnia magna : 92.7 mg / l
No data available
Bioaccumulation
• Spinosad
No data available Formulated product classified as environmentally hazardous and a marine pollutant
Section 13 - Disposal Considerations
Disposal : Dispose of empty containers by wrapping with paper and putting in the garbage .
Section 14 - Transport Information
Road and Rail Transport : Not classified as Dangerous Goods for Transport by Road and Rail
Marine Transport : Classified as Dangerous Goods for Marine Transport
Proper Shipping Name :
ENVIRONMENTAL
HAZARDOUS
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