UAB Cardiothoracic Surgery Annual Report 2015-16 UAB Medicine Cardiothoracic Surgery 2015/16 Annual | Page 23

EXTRACORPOREAL MEMBRANE OXYGENATION The number of ECMO cases has increased dramatically from 10 patients in 2011 to 95 patients supported in 2015. UAB’s ECMO service has rapidly expanded, thanks to an increased focus on pulmonary ECMO support. Our ECMO hospital survival rate increased from 30% in 2011 to 64% in 2015. GENERAL CONDITIONS REQUIRING ECMO TRANSPLANT & MECHANICAL CIRCULATORY SUPPORT Extracorporeal membrane oxygenation (ECMO) is a temporary mechanical support system that facilitates heart and lung function and is utilized extensively at UAB for patients with cardiac or respiratory failure. UAB has maintained an active adult ECMO presence for the past 15 years and has one of the largest ECMO programs in the United States. The program is a collaborative effort between cardiothoracic surgery, pulmonary medicine, and advanced heart failure cardiology, and it requires a team of dedicated perfusionists and nurses. • Veno-venous (VV) ECMO for pulmonary indications: flu, trauma, other respiratory failure, bridge to or from lung transplant • Veno-arterial (VA) ECMO for cardiovascular indications: post-cardiotomy, cardiogenic shock ECMO Volumes and Percent Survival to Hospital Discharge: 2014 – 2015 Etiology: Respiratory 50 35 28 30 20 0 48 44 40 10 Etiology: Cardiology 9 15 73% 89% 49% 35% Bridge to Lung Transplant Cardiogenic Shock 67% Flu 33% Trauma Other Respiratory Failure PostCardiotomy n % Survival to Hospital Discharge RATIONALE FOR AMBULATORY ECMO: • Upright patients who are ambulatory and socially interactive provide the most effective vehicle for clinical recovery or subsequent bridge to transplant. • No lung disease or pulmonary injury benefits from paralysis, sedation, and intubation with non-physiological positive pressure ventilation. www.uabmedicine.org 21