The Little Book of Irish Science SFI Little Book of Irish Science | Page 69

A New Weapon 66 Researchers at the Science Foundation Ireland funded Microbiome Institute in University College Cork and Teagasc Moorepark have found a new antimicrobial agent, Thuricin CD, that can kill the antibiotic- resistant bacterium Clostridium diffi cile, which poses a major problem in clinical and healthcare settings. The new antibiotic may also reduce the risk of disease recurrence, compared with that of broad-spectrum antibiotic treatment, because it spares the normal gut bacteria that help to limit C. diffi cile growth. Thuricin CD was discovered by screening over 30,000 bacteria isolated from the human gut and the technology has been licenced to a recently formed spin-out company, Artugen Therapeutics. apc.ucc.ie