The Leaf THE LEAF January-February 2018 | Page 4

Study: 60 Percent of Tuberous Sclerosis Complex Patients Who Used CBD Products Saw Significant Reduction of Seizures A new study has found promising results in CBD oil used as a treatment for patients suffering from seizures—primarily people with Tuberous Sclerosis Complex. Results from the trial showed that 60 percent of participants who used CBD products saw a clinically significant (80-100 percent) reduction in the frequency of their seizures. The recent clinical study was conducted by renowned Mexico neurologist, Dr. Carlos G. Aguirre-Velazquez. Mexico’s advancements in medical cannabis made international headlines this summer after the State of Mexico announced it would provide cannabidiol (CBD) oil to citizens. Dr. Stuart Titus, CEO of Medical Marijuana, Inc. said “We applaud Dr. Aguirre for his work in unveiling, like he did in this study, that not only is CBD effective in relieving seizures, but also exhibiting that CBD can be used over long periods of time without harm, compared to antiepileptic or broad-spectrum steroids that can have dangerous side effects if used for several years, including vision and damage to major organs.” Patients with varying forms of epilepsy participated in the trial, with the majority having TSC, a genetic disorder characterised by the growth of noncancerous (benign tumours) in many parts of the body, including the brain, which can lead to convulsive crises. TSC affects 1 million people worldwide, 50,000 in the U.S. and 20,000 in Mexico. Research targeted the reduction in frequency, intensity and duration of convulsive crises in people with tuberous sclerosis complex. Other factors observed in the study were quality of life, dependence on heavy prescription drugs and long-term sustainability of treatment with CBD. Additionally, quality of life metrics such as mood, appetite and cognition saw substantial increases among the patients using CBD. Finally, no serious side effects were reported, only mild ones such as drowsiness and increase in appetite, which eventually disappeared with the need to reduce the dose.