The Joys and Woes of Clinical Trial Startup

World Population by Region1 344 Million North America 591 Million 435 Million 292 Million Eastern Europe* Western/Central Europe 1.01 Billion 4.12 Billion Asia Pacific*** Africa Latin America** Many of these roughly 6 billion people are clustered in cities. For example, 77% of the Latin America population lives in a metropolitan area,2 and that percentage grows to 85% in Brazil.19 Initiating a trial in just four Latin American cities (Buenos * ncludes Belarus, Bulgaria, Czech I Republic, Hungary, Moldova, Poland, Romania, Russia, Slovakia, and Ukraine ** Includes Central and South America *** Includes Middle East Aires, Mexico City, Rio de Janeiro, and Sao Paulo) allows access to 10% of the region’s population (or approximately 59 million people).2 clinipace.com 5

The Joys and Woes of Clinical Trial Startup | Page 6