The Journal of the Arkansas Medical Society Issue 3 Vol 115 | Page 13

AFMC: A CLOSER LOOK AT QUALIT Y CONTROLLING CKD PROGRESSION The first step is to identify high-risk patients and attempt to reduce the modifiable risk factors such as smok- ing or obesity. Treat the underlying etiology of CKD by controlling diabe- tes, hypertension and using antipro- teinuric medications. Nephrology referral is critical. Referring patients to dieticians and CKD education pro- grams also helps to slow progression. 6 If unable to control progression, patients must understand their remaining options: dialysis, kidney transplant and palliative care. Dialysis can be provided via differ- ent paths: • In-Center Hemodialysis (IHD), the most common and expensive, involves three- to four-hour treatments, three times weekly. • Home Dialysis (HOD) provides patient autonomy, diet liberalization, ability to continue employment and the convenience of home. HOD provides better clinical outcomes and patient satisfaction and saves about $19,000 per patient, per year. It most closely mimics the body’s natural physiological renal clearance, with more frequent and longer dialysis. • HOD can be administered via peritoneal dialysis (PD), using the peritoneal membrane as a filter; no blood or needles are involved. • Home hemodialysis (HHD) usually provides shorter but more frequent dialysis using patient-friendly machines. Kidney transplantation can be performed with a living or deceased donor. Outside of patients with cirrhosis, most individuals with eGFRs below 20 mL/min/1.73m2 are eligible for possible transplantation. Most transplants occur after patients are on dialysis. Preemptive kidney transplant can occur before the patient needs dialysis. Early referral for transplant evaluation is important. Palliative care discussions can be part of the patient and family discussion about treatment goals. For some patients, the burden of chronic disease or frequent hospitalizations prevents an acceptable quality of life. Renal failure compounds this situation and for some patients, dialysis does not increase quality of life or longevity. Awareness of CKD is low. In a large managed-care cohort of CKD patients, stages 3-5, physician documenta- tion was 14.4 percent. 7 In a survey of high-risk, urban, African-American adults, less than 3 percent named kidney disease as an important health problem, compared to 61 percent and 55 percent naming hypertension and diabetes, respectively. 8,9 Even among patients with stages 4-5 CKD, less than half were aware of their disease. IMPROVING CKD-PATIENT CARE: 1. At the primary care level, recognize high-risk patients, assess GFR using urine dipstick for proteinuria/ albuminuria and have the lab calculate eGFR. 2. Involve nephrology care as soon as appropriate. 3. Optimize care using CKD management guidelines, produced and freely accessible from KDIGO. 4. Know the options for CKD control and ESRS management. The UAMS Division of Nephrol- ogy and Arkansas Department of Health’s Chronic Disease Branch are working to increase CKD aware- ness and support CKD education. The Arkansas State Chronic Kidney Disease Advisory Committee (ARCK- DAC) is a collaboration of multiple governmental agencies, renal groups, nonprofits and patient advocates. Its goals are to improve awareness, detection and education through community engagement. The AFMC has ongoing initiatives for similar goals, including grassroots health education for CKD patients. s The authors practice in the Division of Nephrology, Deptment of Internal Medicine, UAMS. REFERENCES 1. Centers for Disease Control and Prevention. Chronic Kidney Disease Surveillance System Website. http:// www.cdc.gov/ckd. Accessed 6-29-18. 2. Kazancioğlu R. Risk factors for chronic kidney disease: an update. Kidney Inter- national Supplements. 2013;3(4):368- 371. doi:10.1038/kisup.2013.79. 3. Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. KDIGO 2012 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. Kidney Int. Suppl. 2013;3:1-150. 4. Gorodetskaya I, Zenios S, McCulloch CE, et al. Health-related quality of life and estimates of utility in chronic kidney disease. Kidney Int. 2005;68(6):2801- 2808. doi: S0085-2538(15)51188-5. 5. Davison SN. End-of-life care preferences and needs: Perceptions of patients with chronic kidney disease. Clin J Am Soc Nephrol 5: 195–204, 2010. 6. Weis L, Metzger M, Haymann J, et al. (2013) Renal function can improved at any stage of CKD. PloS ONE 8(12)e81835.doi: 10.1371/journal. pone.0081835 7. Guessous I, McClellan W, Vupputuri S, et al. Low documentation of chronic kidney disease among high-risk patients in a managed care popula- tion: a retrospective cohort study. BMC Nephrol. 2009;10:25. doi: 10.1186/1471- 2369-10-25. 8. Waterman AD, Browne T, Waterman BM, et al. Attitudes and behaviors of African Americans regarding early detection of kidney disease. Am J Kid- ney Dis. 2008;51(4):554–562. 9. National Health and Nutrition Exam- ination Survey (NHANES), 2001-2012 participants aged 20 & older. NUMBER 3 SEPTEMBER 2018 • 61