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DENTAL CARIES Cite this article: Javed F, Romanos GE. A comprehensive review of various laser-based systems used in early detection of dental caries. Stoma Edu J. 2015;2(2):108-113. A COMPREHENSIVE REVIEW OF VARIOUS LASER-BASED SYSTEMS USED IN EARLY DETECTION OF DENTAL CARIES Fawad Javed1a Georgios E. Romanos2b* Division of General Dentistry, Eastman Institute for Oral Health, University of Rochester, NY 14620, USA. 2 School of Dental Medicine, Stony Brook University, Stony Brook, NY, USA. 1 BDS, PhD, Research Associate b DDS, DMD, PhD, Professor a Received: July, 1st 2015 Accepted: July, 14 2015 * Corresponding author: Professor Georgios E. Romanos School of Dental Medicine Stony Brook University, Stony Brook, NY, USA Tel: +1 (631) 632-8755 Fax: +1 (631) 632-8670 Email: [email protected] 108 Abstract Introduction: The aim was to comprehensively review the various laser-based systems used in early detection of dental caries. Methodology: PubMed/Medline and Google-scholar databases were searched from 1995 up to June 2015 using various combinations of the following keywords: “dental early caries”, “diagnosis”, “laser” and “light fluorescence” (LF). Literature reviews, letters to the Editor, and commentaries were excluded. Articles published only in English were included. The pattern of the present study was customized to primarily summarize the pertinent information. Results: Laser fluorescence at 655 nm (DIAGNOdent) is a promising tool for early detection of occlusal caries. Other systems based on the LF concept include VistaProof (VP) and DIAGNOdent Pen; however, no statistically significant difference in the caries detection efficacy has been reported between VP, DIAGNOdent Pen and DIAGNOdent devices. Although light emitting diode systems have also been tested for detecting caries, their diagnosing efficacy remains unclear due to a lack of studies. Conclusion: Lasers-based caries detection systems are useful tools in the early detection of caries in contrast to traditional visual and radiographic examination techniques; however, further studies are needed to assess the caries diagnostic efficacy of the various commercially available laser-based caries diagnostic systems. Keywords: dental early caries, diagnosis, laser and light fluorescence, light emitting diode Introduction Dental caries (or caries) represent a chronic disease of the mineralized tissues of teeth, namely (enamel, dentin and cementum) caused by the action of cariogenic bacteria on fermentable carbohydrates leading to the demineralization of these mineral portions and (if left untreated) disintegration of their organic matrix.1 Traditionally, caries are diagnosed by visual clinical examination (for example, visualizing the size and depth of the lesion using mechanical probes) and radiographs (such as bite-wing images)2; however, these techniques are able to detect carious lesions only at an advanced stage.3 Yet, specificity of visual examination for the diagnosis of caries has been reported to be high; the methodology exhibits low sensitivity and reproducibility.4 Likewise, although digital radiography (such as digital intra-oral and extra-oral radiographs and three-dimensional computed tomography) is a modernization in imaging technology 5-7; the potential risk of radiation hazards associated with these techniques, remains inevitable. Novel techniques have been assessed as diagnostic tools to identify and quantify initial demineralization. Laser fluorescence (LF) (in the visible region, blue or red) has been reported to be a valuable tool for early diagnosis of caries.8,9 Caries detecting devices based on the LF mechanism include DIAGNOdent 2095 and DIAGNOdent 2190 (LF and LFpen, KaVo, Biberach, Germany). Results by Takamori et al. 10 showed that LF is useful in the early diagnosis of occlusal caries. LF has also shown promising results in the detection of caries in deciduous teeth. 11,12 Likewise, other LF-based devices comprising of a light-emitting-diode (LED) STOMA.EDUJ (2015) 2 (2)