StomatologyEduJ 5(1) SEJ_4-2017r | Page 26

KNOWLEDGE AND PATTERNS OF ANTIBIOTIC PRESCRIPTION AMONG DENTAL PRACTITIONERS IN HAIL, SAUDI ARABIA 256 tests, inappropriate duration, lack of guidelines and patients’ demand and expectations. In this study, all descriptive data were projected as frequencies and percentages and compared using chi-squared test, while quantitative data were presented as means and standard deviations (SD) and compared using t-test. 3. Results A hundred and one completed questionnaires were considered valid. Any questionnaire with missing or insufficient data were excluded. The response rate was 67%. Males represented 85.1% of the respondents, while females represented 14.9%. The demographic and professional characteristics of the respondents are shown in Table 1. Most of the participants were general practitioners or interns (66.3%), specialists (30.7%) and only a few were consultants (3%). Nearly 60% of the participants practiced dentistry for more than 5 years. Indications for antibiotic prescription in relation to the clinical signs and symptoms and general considerations by the practicing dental surgeons are demonstrated in Table 2. Most of the dental practitioners would prescribe antibiotics if there is a sign of fever (86.1%), swelling causing eye closure (90.1%) or diffuse swelling (75.2%). A considerable percentage would prescribe antibiotics for a localized fluctuant swelling (55.4%). Patients presented with difficulty in swallowing would be given antibiotics by 56.4% of the participant dental surgeons. A significant percentage (52.2%) of dental practitioners would prescribe antibiotics postoperatively to prevent potential complications. In cases where the diagnosis is inconclusive or a decision to postpone the treatment has been taken, 44.6% and 75.2% of the participants would prescribe antibiotics respectively. Table 3 demonstrates the patterns of antibiotic prescription by the participants for the clinically diagnosed conditions. The table reveals diverse variation among the respondents. The respondents would consider antibiotic therapy for pericoronitis, cellulitis and trismus by 68.3%, 89.1% and 40.6% respectively. A large percentage of the respondents (73.4%) would still prescribe antibiotics for surgical extraction, whereas 34.7% of the respondents would consider the same for routine extraction. Treatment of dry socket by antibiotics is a choice of 48.5% of the respondents. Acute periapical infection and acute pulpitis both are considered for antibiotic therapy by 57.4% and 38.6% of the respondents, respectively. Dental infection may be manifested as maxillary sinusitis. About 67% of the dental professionals would prescribe antibiotics for such conditions. Substantial percentages of dental surgeons (70.3%) and (60.4%) would use antibiotics in treatment of periodontal abscesses and ulcerative gingivitis, respectively. Nearly 52% of the respondents are inclined to use antibiotics in treatment of chronic periodontitis. About 89% of the respondents would prescribe antibiotics for cellulitis and 68.3% for pericoronitis cases. Patients with trismus would be prescribed antibiotics by approximately 41% of the dental surgeons. Post root canal treatment apical surgeries are common procedures. Antibiotic therapy is considered for apicectomy by 65.3% of the respondents. A considerable percentage of dental surgeons (61.4%) would prescribe antibiotics for root canal surgery postoperatively, whereas 41.6% would do the same preoperatively. Less than 24% of the dental surgeons would probably prescribe antibiotics for scaling and polishing, direct pulp capping and indirect pulp capping cases. Antibiotic therapy is considered by 56.4% of the respondents in case of teeth replantation. Table 4 indicates the motivation for using certain antibiotics in treatment of specific clinical conditions. Out of the 6 listed antibiotics, amoxicillin remains the drug of choice in management of all clinical conditions. Probably, amoxicillin-clavulanate is the second drug of choice after amoxicillin in treatment of cellulitis. The respondents are not inclined to use a combination of antibiotics in their routine dental treatments. The table shows that tetracycline and cephalosporins were scarcely prescribed by the dental surgeons. The study has assessed the dental practitioners’ opinions regarding the contributing factors in development of antibiotic resistance (Fig. 1). More than 65% of the respondents thought that wide spread use of antibiotics is a very important contributing factor in development of antibiotic resistance. Inappropriate antibiotic course duration was rated as the second among the very important contributing factors. Moreover, about 52% of the respondents thought that use of broad spectrum antibiotics and lack of Table 1. Demographic and professional characteristics of practicing dental practitioners. Variable n (%) Gender: Male 86 (85.1) Female 15 (14.9) Age (years): 20-29 28 (27.7) 30-39 35 (34.7) 40-49 32 (31.7) 50-59 06 (05.9) Professional rank: General practitioner/Intern 67 (66.3) Specialist 31 (30.7) Consultant 03 (03.0) Years in practice: < 5 years 41 (40.6) > 5 years 60 (59.4) Stoma Edu J. 2017;4(4): 254-263 http://www.stomaeduj.com