Senwes Scenario December 2018 / January 2019 | Page 22

AGRICULTURAL Nutrition and Immunity of Feedlot Cattle Is special handling and nutrition necessary? A healthy animal give the best production results and a sick animal causes directly and indirectly unnecessary costs. The immune system accounts for a minor portion of total nutritional requirements in the healthy animal but in response to an immune challenge has a major impact on nutritional status and requirements for specific nutrients.  By dr Kobus Swart Animal Nutrition Specialist N utrient deficiencies increase susceptibility to most infec- tious diseases and increase the probability of secondary infections. Vitamins or trace minerals deficiencies significantly depress immune function and resistance to stress even when animals are otherwise well fed with sufficient energy and protein. Nutrition has the largest impact on morbidity and mortality during the first month after arrival at the feedlot. WHAT IS THE PROBLEM? The immune system is suppressed in stressed cattle, contributing to the high incidence of respiratory disease in the first 30 to 45 days on feed. Lungs of healthy cattle can resist challenge from surprising- ly large numbers of bacteria. But when the animal is stressed, relatively small num- bers of bacteria can result in pneumonia. 20 An additional aspect during this early stage is to adapt the rumen to easy digestible (starch) feed. If this process is not managed well, metabolic disturbances (acidosis) can easily occur. This causes a decline in intake, permanent damage to the rumen wall, dehydration and poor digestibility of ingested feed which impos- es a huge challenge to the immunity of the animal. Nutrition has the greatest impact on immunity during the first two to four weeks after arrival at the feedlot, even more so in the first few days after arriv- al. A problem is to get enough nutrients into cattle, particularly those that need it the most. Providing key nutrients can reduce stress-induced weight loss and immune suppression, improve weight gain and reduce morbidity and mortality from bovine respiratory disease. WHAT IS IMMUNITY TO INFECTION? Animals resist infection using non-specific mechanisms (‘innate’ immunity) and spe- cific mechanisms (acquired immunity). SENWES SCENARIO | TECHNOLOGY & INNOVATION 2018 Innate immunity includes epithelial tissue which covers body surfaces (example skin or hide, hoof, cornea) and lines body cavities (respiratory, urogenital, gas- tro-intestinal) is a physical barrier to keep infectious agents from entering the body. Acquired immunity is where exposure to a foreign substance (antigen) results in the development of immune cells and antibodies specific against that particular antigen only. Specific immunity takes time to develop, and therefore is effective in preventing infection only if the animal was previously exposed to that antigen. A nutrient deficiency does not affect all immune mechanisms equally, nor does it always affect the same mechanism equally for different antigens. A group of deficient animals may have adequate antibody responses to some antigens (or vaccines), and depressed antibody responses to other antigens. Similarly, under practical conditions, deficient ani- mals may be more susceptible to some but not all disease causing organisms. That is why the symptoms of disease are