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Volume 22 • Issue 01 • 2018 on cow performance and milk production , Olmix developed a product known as DigestSea to help prevent both clinical and subclinical ketosis . It contains the algae sulfated polysaccharide known as MSPLIPID which has been shown to improve liver function and lipid metabolism . This is due to MSPLIPID interacting with Farnesoid X Receptors ( FXR ) which are found in the liver and intestinal cells . FXR is a key receptor for cholesterol , bile acids and lipid ( triglycerides ) metabolism . Adding MSP to an animal ’ s diet increases FXR expression by 3 fold . The exact mechanism of action is complex but the end result is detoxification of the liver , by improving the conversion of NEFA ( non esterified fatty acids ) into VLDL ( very low density lipoprotein ) which are directed to the udder instead of being used in the Krebs cycle and resulting in the production of ketone bodies . This results in decreased ketone body production and prevention of both clinical and subclinical ketosis . Field studies with cows that received DigestSea for 5 days post-calving showed that all of the treated cows had blood BHBA levels below 1.2 mMol / L while several of the control cows experienced clinical or subclinical ketosis .
Boosting immunity In addition to ketosis management and improving gut health , controlling herd immunity is another advantage of using algae extracts in dairy feed . The algae sulfated polysaccharide known as MSPIMMUNITY has been incorporated into Olmix ’ s product called Searup . Studies conducted in collaboration with the French Institute of Agronomic Research ( INRA ) showed that MSPIMMUNITY can modulate the immune system by stimulating the expression of immune mediators ( cytokines and chemokines ) by intestinal epithelial cells .
These immune mediators favor the proliferation ,
differentiation , and recruitment of immune cells involved in innate and adaptive immunity . This suggests that MSPIMMUNITY may be used to activate an immune response in the animal with the aim of improving their natural defenses and reducing the use of antibiotics on farms . Using this product during times of stress , such as weaning or movement to a new group of animals , can improve the functionality of the immune system and potentially decrease the incidence of diseases such as diarrhea and pneumonia . Modern dairy cows receive many vaccinations throughout their life , but many farms still struggle with respiratory problems during periods of environmental stress . This environmental stress , along with the immune suppression that comes with high production and possible mycotoxin contamination of feed , can lead to a failure of the cow ’ s ability to respond properly to vaccination .
Providing Searup to cattle at the time of vaccination can help to alleviate this immune suppression , increase the immune response to the vaccine , and give better protection against disease .
The dairy industry , similar to swine and poultry , is under pressure from both consumers and regulatory agencies to decrease the use of antibiotics . Algae sulfated polysaccharides in the form of MSPMUCIN , MSPLIPID , and MSPIMMUNITY provide efficient strategies to control digestive problems , prevent ketosis , and reduce suppression of the immune system .
Products containing these compounds can play an important role in helping to achieve this goal of reducing the use of antibiotics . An additional benefit is that we are utilizing an abundant and renewable resource , and extracting unique , biologically active compounds that help animals to be healthier and more productive .
Vitam International is a leader in providing scientific proven feed additives and services in Sub-Sahara Africa . We make a significant contribution to the agricultural feed industry by supplying world class technology supported by highly qualified and skilled personnel with a global network of technical support . Please contact Vitam International for more information on Olmix products
Hermann van der Westhuizen | Cell : 082 356 7022 | Tel : + 27 ( 12 ) 665 5245 | Email : hermannw @ vitam . co . za www . vitam . co . za
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