Interventional Cardiology
MULTICENTER REGISTRY OF CHRONIC TOTAL OCCLUSION INTERVENTIONS
Local Principal Investigator : James W . Choi , MD , FACC , FSCAI Project description : Percutaneous coronary intervention ( PCI ) of chronic total occlusions ( CTOs ) is increasingly being performed in patients with advanced coronary artery disease , but there is limited information on the techniques utilized and the procedural outcomes . The goal of this multi-center , investigator initiated registry is to collect information on treatment strategies and outcomes of consecutive patients undergoing CTO PCI among various participating centers . This study was by invitation only and includes the best centers across the U . S . for CTO PCI . The information collected will be used to determine the frequency of CTO PCI performed at the participating sites and examine the procedural strategies utilized , and the procedural ( both immediate and during follow-up ) outcomes . Primary and secondary endpoints : The primary endpoint is procedural success during CTO PCI . Secondary endpoints are technical success and incidence of major cardiovascular events following CTO PCI .
Specialized Interventional Procedures
Angioplasty related interventional procedures are a mainstay at Baylor Hamilton Heart and Vascular Hospital . Other terms commonly associated with angioplasty are percutaneous coronary intervention ( PCI ), balloon angioplasty , coronary angioplasty , coronary artery angioplasty , percutaneous transluminal coronary angioplasty and heart artery dilatation . One of the areas that cardiologists on the medical staff at Baylor Hamilton Heart and Vascular Hospital are known for is the ability to treat patients with left main disease .
MEASURING INNOVATION IN HEART AND VASCULAR CARE
Patients with advanced coronary artery disease who have undergone various procedures may be diagnosed with “ unprotected ” left main ( ULM ) disease . These candidates are referred to the interventional cardiologists on the medical staff for advanced treatment and procedures that have been refined through years of research and innovation . With many clinical trials over the years involving drug-eluting stents , left main disease can be treated at Baylor Hamilton Heart and Vascular Hospital with experienced and skilled interventionalists .
Other services available to patients include :
• Advanced generation of stents
• Atrial septal defect ( ASD ) and patent foramen ovale ( PFO ) closure
• Balloon valve repair
• Cardiac assist devices – a variety of assist devices are offered including the potential for patient enrollment in device studies
• Carotid stenting – many of the recentto-market stents were trialed at Baylor Hamilton Heart and Vascular Hospital
• Coronary angioplasty and stenting
• Coronary atherectomy
• Peripheral angiography and angioplasty
• Peripheral atherectomy
• Unprotected left main disease intervention
Physicians on the medical staff have published numerous articles on important research regarding cardiac stents . The first drug-eluting stent in Texas was placed in our catheterization lab as part of the very early years for the SIRIUS trial .* The history of “ firsts ” continued in fiscal year 2017 with many first-to-market post-FDA approval stents and valves .
Trials in fiscal year 2017 have included :
• Treatment of coronary artery disease with the newest generations of drug-eluting stents
• New dosing strategies for medications used to prevent clots in stents
• Gene therapy for coronary disease not treatable with balloons and stents
• Treatment of stenosis in the renal ( kidney ) arteries in patients with refractory high blood pressure
• New devices and stents to treat peripheral arterial disease
• Stents for the carotid arteries
• Closure for atrial septal defects and patent foramen ovale
* SIRIUS clinical trial : Baylor Hamilton Heart and Vascular Hospital was an original site . Trial was open from 2000 to 2005 .
34