Clinical Trials and Studies
Clinical Trials and Studies
ADAPTABLE – Aspirin Dosing : A Patient-Centric Trial Assessing Benefits and Long-term Effectiveness . Primary Investigator : Peter McCullough , MD
Absorb™ BVS – Randomized controlled trial , a clinical evaluation of Absorb™ BVS , the Everolimus Eluting Bioresorbable Vascular Scaffold in the treatment of subjects with De Novo native coronary artery lesions . Primary Investigator : James W . Choi , MD
Alternative to Curative Ablation – Efficacy , safety and durability of response to dofetilide in patients with atrial fibrillation : alternative to curative ablation . Primary Investigator : Peter Wells , MD
AME Post RANA – Autonomic and metabolic evaluation post renal artery nerve ablation . Primary Investigators : Cara East , MD , Eric Howden , PhD
Angiographic Patterns of Myxoma – Primary Investigator : Carlos E . Velasco , MD
Angiography vs Angiography with IVUS – A prospective randomized feasibility trial comparing angiography and angiography with IVUS for treatment of hemodialysis access failures . Primary Investigator : William Shutze , MD
Aortic Valve Replacement – Aortic Valve Replacement for Low Gradient Aortic Stenosis . Primary Investigator : William C . Roberts , MD
ATS Post Approval ( 3f PAS ) – Primary Investigator : Robert F . Hebeler , Jr ., MD
AV Node Reentry Tachycardia – Left Septal Slow Pathway Ablation in Patients with AV Node Reentry Tachycardia . Primary Investigator : Peter Wells , MD
Balloon Temperature – Association between balloon temperature and real-time pulmonary vein isolation during cryoballoon ablation for atrial fibrillation . Primary Investigator : Robert Kowal , MD
Baylor Extracorporeal Membrane Oxygenation Research Program . Primary Investigator : Brian Lima , MD
Baylor Hypertrophic Cardiomyopathy Program Development Project – Time-resolved , 3D phase contrast magnetic resonance imaging ( MRI ) ( 4D Flow ) and Advanced Strain Rate Echocardiography in Patients with Hypertrophic Cardiomyopathy . Primary Investigator : Peter A . McCullough , MD
BioFlow-V ; BIOTRONIK – A prospective randomized multicenter study to assess the safety and effectiveness of the orsiro sirolimus eluting coronary stent system in the treatment of subjects with up to three de novo or restenotic coronary artery lesions . Primary Investigator : James Choi , MD
Blood Biomarkers for Patients with Advanced Heart Failure – Assessment of multiple blood biomarkers in patients with advanced heart failure undergoing evaluation for cardiac transplantation and mechanical circulatory support . Primary Investigator : Jose Mendez , MD
Blood Biomarkers for Patients with Chronic Heart Failure – Assessment of multiple blood biomarkers in the personalized management of chronic heart failure . Primary Investigator : Peter A . McCullough , MD
Bio-electrical Impedance Spectroscopy in Heart Transplantation . Primary Investigator : Brian Lima , MD
Burden of Cardiovascular Events following Percutaneous Coronary Intervention . Primary Investigator : Anupama Vasudevan
CAFS – Cryoablation Atrial Fibrillation follow-up study . Primary Investigators : Robert Kowal , MD , Cara East , MD
CANTOS Trial – A randomized , double-blind , placebo-controlled , event driven trial of quarterly , subcutaneous canakinumab in the prevention of recurrent cardiovascular events among stable postmyocardial infarction patients with elevated hsCRP . Primary Investigator : Cara East , MD
Cardiac Adiposity – Massive cardiac adiposity at necropsy . Primary Investigator : William C . Roberts , MD
Cardiac Rehabilitation for a 39-year-old Skydiver Status-post Ascending Aortic Aneurysm Repair , Aortic Valve Replacement and Implementation of a Dual Chambered Pacemaker . Primary Investigator : Jenny Adams , PhD
Cardiac Transplantation : Reasons for cardiac transplantation . Primary Investigator : William C . Roberts , MD
CardioMEMS – Impact of using CardioMEMS for Heart Failure ( HF ) Patients in a Large Health Care System : A Registry . Primary Investigator : Shelley Hall , MD
Causes of bioprosthetic and mechanical prosthetic dysfunction in the mitral and aortic valve positions . Primary Investigator : William C . Roberts , MD
Causes of death in patients studied at necropsy at BUMC , 2013-2015 . Primary Investigator : William C . Roberts , MD
COAPT Trial – Clinical Investigational Plan 11-512 – Cardiovascular outcomes assessment of the MitraClip Percutaneous Therapy for heart failure patients with functional mitral regurgitation . Primary Investigator : Paul Grayburn , MD
Cobra PZF™ Coronary Stent System – Cobra PZF™ in native coronary arteries for early healing , thrombus inhibition , endothelialization and avoiding long-term dual anti-platelet therapy . Primary Investigator : Robert Stoler , MD
Commonalities of cardiac rupture – Left ventricular free wall , ventricular septum , or papillary muscle during acute myocardial infarction secondary to atherosclerotic coronary artery disease . Primary Investigator : William C . Roberts , MD
Contribution of Chronic Kidney Disease and Acute Kidney Injury to Heart Failure Outcomes . Primary Investigator , Kristen Tecson , PhD
CUP – Alirocumab Expanded Access Program for the Treatment of Patients with Severe Hypercholestolemia not controlled with maximal tolerated dose of lipidlowering therapy administered according to standard of care . Primary Investigators : Cara East , MD ,
Peter A . McCullough , MD CV Surgery Data Outcomes Collection . Primary Investigator : Gonzalo Gonzalez-Stawinski , MD
Determinants of Conduction System Abnormalities and the Need for Permanent Pacing after Transcatheter Aortic Valve Replacement . Primary Investigator : Timothy Ball , MD
Diet Pattern in Women at High Cardiometabolic Risk and CVD . The association between diet pattern among women at high cardiometabolic risk and cardiovascular disease ( CVD ) incidence and mortality rate . Primary Investigators : Hyun Shin , MD , Peter A . McCullough , MD
DREAM – A Double-Blind , Randomized , Sham- Procedure-Controlled , Parallel-Group Efficacy and Safety Study of Allogeneic Mesenchymal Precursor Cells ( rexlemestrocel-L ) in Patients With Chronic Heart Failure Due to Left Ventricular Systolic Dysfunction of Either Ischemic or Nonischemic Etiology : DREAM HF-1 . Primary Investigator : Cara East , MD
Echo Image Quality – Improving the quality of echocardiographic imaging measurements in the diagnosis of severe aortic stenosis . Primary Investigator : Paul Grayburn , MD
Effect of Post-Diabetic Diet Pattern on Mortality . The Effect of Post-Diabetic Diet Pattern on Mortality Among Type 2 Diabetic Women in Nurses ’ Health Study ( NHS ) – Priori Dietary Pattern ( Dietary Quality Score ) Methods ( Project # 1 ) and Posteriori Dietary Pattern Methods ( Project # 2 ). Primary Investigator : Hyun Shin , MD , Peter A . McCullough , MD
Electrocardiographic total 12-lead QRS voltage in patients having operative resection of syphilitic aortic aneurysm . Primary Investigator : William C . Roberts , MD
Evaluation of XIENCE PRIME™ or XIENCE V ® versus Coronary Artery Bypass Surgery for Effectiveness of Left Main Revascularization . Primary Investigator : James W . Choi , MD
EVEREST II Study – A Study of the Evalve Cardiovascular Valve Repair System ( CVRS ) Endovascular Valve Edge-to-Edge Repair . Primary Investigator : Paul Grayburn , MD
EVOLVE II – A Prospective Multicenter Trial to Assess the Safety and Effectiveness of the SYNERGY™ Everolimus-Eluting Platinum Chromium Coronary Stent System ( SYNERGY™ Stent System ) for the Treatment of Atherosclerotic Lesion ( s ). Primary Investigator : Robert Stoler , MD
EVOLVE Short DAPT – A prospective , multicenter , single-arm study designed to assess the safety of 3-month dual antiplatelet therapy ( DAPT ) in subjects at high risk for bleeding undergoing percutaneous intervention . Primary Investigator : Robert Stoler , MD
Excised circular “ cores ” of left ventricular wall – Usefulness of gross and histologic examination of excised circular “ cores ” of left ventricular wall for diagnostic purposes . Primary Investigator : William C . Roberts , MD
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