action. All ingredients in the mildly mint-flavored gel are safe if
ingested and no abrasives, antimicrobials or detergents were added.
Livionex with activated edathamil is able to penetrate
and disrupt the ability of bacteria to bind to the tooth
surface. It is clinically proven to be up to 3x as effective
as traditional toothpastes at reducing plaque.The Plaque
Index achieved with Livionex averages < 0.5 (compared
to ~2 with regular brushing). Plaque leads to gingivitis,
gingival bleeding and worse, and studies show that reduction of plaque leads to dramatic reductions in gum
inflammation and bleeding.
Three years of rigorous clinical studies of Livionex have documented
superior efficacy at reducing plaque, gingival inflammation, bleeding
on probing and perio pocket depth. Livionex has proven to deliver
exciting results that no other toothpaste has been able to come close
to achieving. Results showed that Livionex was more than 250% better in reducing plaque, and more than 200% better in reducing gum
inflammation and bleeding as compared to the control toothpaste.
Importantly, studies show that Livionex does not etch dental enamel.
Study 1 – Plaque,
Gingivitis and
Bleeding
In the pilot study conducted at a
clinical practice in Milpitas, CA,
patients were randomized to
receive either Livionex or
Colgate Total and instructed to
brush twice a day with a soft
toothbrush. The dentist, hygienist
and patients were blinded
regarding the assignment of the
toothpaste. Comparison of baseline measurements to end of study measurements showed a statistically
significant reduction of plaque, gingivitis and gingival bleeding. Since all
patients received a professional deep cleaning after baseline measurements, all started with a zero on the Plaque Index. In the Colgate Total
group, plaque was reduced by 7%, meaning that 93% of the plaque at
baseline had returned after four weeks. In the Livionex group, there
was a plaque reduction of 91%, which means that just 9% of the plaque
had returned at the end of four weeks.
technician and patient were blinded regarding the assignment of the
toothpaste. Each patient was given a standard soft toothbrush and
instructed to brush twice a day. A comparison of baseline to end of study
measurements showed a statistically significant reduction of plaque, gingivitis and gum bleeding.
Study 3 –
Remineralization ()%