NEO Magazine Issue 2

B) Cytokines can stimulate more cytokine production and cause many more cytokine receptors to awaken. Unchecked, this becomes a cytokine storm showing symptoms of swelling, redness, fatigue, and nausea; even death. Phytocannabinoids have the ability to suppress this inflammatory cytokine cascade by inhibiting glial cell production of the cytokines interferon or interleukin. Here we see the seeds of chronic inflammation dissolved by the modulation process of cannabinoids bringing homeostasis to systems out of balance. This is a good example of how cannabinoids normalize biological processes all throughout the body and allows us to keep that glow of well-being through a long and happy lifetime.(*6) The more one looks into the endocannabanoid system the more one can see the symbiosis between cannabis and humans, a whole article could be dedicated to this alone. However it doesn’t stop there. Other plants and animals from tunicates and nematodes to basically every vertebrate species all have an endocannabinoid system; essential in their adaptation in their environment. Through comparisons in genetics information of cannabinoid receptors in different species, scientists estimate that the endocannabinoid system evolved in primitive animals over 600 million years ago. (*7) Having briefly looked at the properties of this extraordinary plant, one can see how vital Cannabis Sativa Indica Ruderalis is. It has been used for thousands of years as medicine, as food, as building material, and so much more. It’s ability to nourish it’s environment as well as the neighbouring plants and animals; making it possibly the most desirable plant on the face of this earth. The only reason any institution would ban or limit the use of this plant could only be to inhibit ones ability and birth right to maintain health and recover from illness. When obeying the rules means consigning ourselves to death, surely it’s time to stop obeying the rules. With this one plant exists solutions for hundreds of problems facing our world today, from soil toxicity to the cancer epidemic. By increasing the farming or wide spread growth of this plant, we have the ability to literally transform the world we live in for the better. End of Article *1: http://scienceblogs.com/scientificactivist/2009/04/02/ thc-gives-cancer-cells-the-mun/ Published in Volume 119, Issue 5 (May 1, 2009) J Clin Invest. 2009;119(5):1359–1372. doi:10.1172/JCI37948. Copyright © 2009, American Society for Clinical Investigation. http://www.jci.org/articles/view/37948 *2: http://www.csatc.org/botany.html *3: http://www.mhhe.com/biosci/pae/botan...rticle_10.html *4: http://www.encod.org/info/700-MEDICINAL-USES-OF- CANNABIS.html *5: 20. Aviello G, Romano B, Borrelli F, et al.: Chemopreventive effect of the non- psychotropic phytocannabinoid cannabidiol on experimental colon cancer. J Mol Med (Berl) 90 (8): 925-34, 2012. [PUBMED Abstract] 21.Romano B, Borrelli F, Pagano E, et al.: Inhibition of colon carcinogenesis by a standardized Cannabis sativa extract with high content of cannabidiol. Phytomedicine 21 (5): 631-9, 2014. [PUBMED Abstract] *6: Dennis Hill a. http://www.pnas.org/content/103/3/696 b. http://www.cancer.gov/cancertopics/pdq/cam/cannabis/healthprofessional/page1 c. http://cannabisinternational.org/info/NonPsychoactive-Cannabinoids.pdf d. http://www.ncbi.nlm.nih. gov/pubmed/16918439 *7: http://norml.org/library/item/introduction-to-the-endocannabinoid-system *8: Robert Deitch Hemp: American History Revisited: The Plant with a Divided History, 2003 http://medicalmarijuana. procon.org/view.timeline.php?timelineID=000026 *9: http://www.thecannabible.com

NEO Magazine Issue 2 | Page 8