ENDODONTICS
CHRONIC APICAL PERIODONTITIS IN CHRONIC KIDNEY DISEASE PATIENTS
Georgiana Florentina Moldoveanu 1a , Ioana Suciu 1b , Paula Perlea 1c
1
Department of Endodontology , Faculty of Dental Medicine , “ Carol Davila ” University of Medicine and Pharmacy , Bucharest , Romania a
MD , Assistant Professor b
MD , PhD , Associate Professor c
MD , PhD , Associate Professor
Cite this article : Moldoveanu GF , Suciu I , Perlea P . Chronic apical periodontitis in chronic kidney disease patients . Stoma Edu J . 2016 ; 3 ( 1 ): 28-32 .
ABSTRACT
Received : April 13 , 2016 Received in revised form : April 27 , 2016
Accepted : May 3 , 2016 Published online : April 20 , 2016
Introduction : The involvement of oral-dental infectious pathology in triggering or worsening kidney diseases has been known for a long time . The purpose of this study was to evaluate the prevalence of chronic apical periodontitis in a group of chronic kidney disease patients and their relationship with the parameters related to renal function . Methodology : Medical parameters of 51 predialysed adults were extracted from the observation charts of the hospital using a registration form . Chronic apical periodontitis has been diagnosed on periapical radiographs by the presence of any radiolucent areas detected in the apical third of teeth . Results : 29.41 % of patients had no periapical lesion , 33.33 % had one periapical lesion , 17.64 % had 2 periapical lesions and the remaining 19.62 % had at least three periapical lesions . Chronic apical periodontitis was not statistically significantly associated with any of the demographic variables . Lower serum albumin levels were significantly associated with a greater number of periapical lesions . In addition , the large number of chronic apical periodontitis was significantly associated with high values of cholesterol . Conclusion : The detection of some abnormal cholesterol and albumin levels during regular investigations of patients with chronic renal failure , require a mandatory dental visits that will be associated with a radiological examination to detect chronic apical periodontitis . The results obtained in our study emphasize the importance of radiological examinations for all patients , prior to kidney transplantation , since they may have teeth with inflammatory lesions , which cannot be clinically detected . Keywords : chronic apical periodontitis , predialysed patients , cholesterol , albumin .
1 . Introduction
The oral health of patients with chronic kidney disease ( CKD ) has become a subject of intense investigation in recent years , not only due to the oral and systemic manifestations of the disease but also due to treatment-related complications . Moreover , the chronic kidney disease is a disease whose incidence is steadily increasing and as a result , a large number of patients are seeking dental care . The possibility that events in the oral cavity may influence systemic diseases has been highlighted by numerous studies on associations and interactions between oral diseases and cardiovascular diseases , myocardial infarction , manifestations during pregnancy , diabetes , and bacterial pneumonia . Research conducted has included epidemiological studies , intervention studies and studies that have attempted to elucidate the mechanisms of action . The results were occasionally contradictory , which is not surprising , given the variations in study designs , populations studied and the statistical analysis used for the studies . 1 The involvement of oral-dental infectious pathology in triggering or worsening kidney diseases has been known for a long time . 2 Most evidence gathered involve infectious outbreak , located in the oral cavity , ingravescence of chronic glomerulonephritis with mesangial deposits of IgA , but also in updating and increasing the rate of other renal diseases progression . In this context , the identification of sources of inflammation in patients with CKD and their removal is a matter of great interest in nephrology but also in cardiology
* Corresponding author : Assoc . Prof . Paula Perlea , MD , PhD 57 Levantica Str ., District 3 , RO-031402 Bucharest , Romania Tel : + 40744 377 011 , Fax : + 40213468888 , e-mail : paula . perlea @ gmail . com
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