Masters of Health Magazine April 2019 - Page 84

6. CBD Oil May Treat Seizures and Other Neurological Disorders

A 2014 survey conducted by researchers at Stanford University was presented to parents belonging to a Facebook group dedicated to sharing information about the use of cannabidiol-enriched cannabis to treat their child’s seizures.

Nineteen responses met the inclusion criteria for the study: a diagnosis of epilepsy and current use of CBD-enriched cannabis. The average number of anti-epileptic drugs tried before using CBD cannabis was 12. Sixteen (84 percent) of the 19 parents reported a reduction in their child’s seizure frequency while taking CBD cannabis. Of these, two (11 percent) reported complete seizure freedom, eight (42 percent) reported a greater than 80 percent reduction in seizure frequency, and six (32 percent) reported a 25–60 percent seizure reduction.

Other beneficial effects included increased alertness, better mood and improved sleep; while side effects included drowsiness and fatigue.

Later in 2014, researchers reported on preliminary study results involving children with treatment-resistant epilepsies in an expanded access “compassionate use program.” Patients received a purified 98 percent oil-based CBD extract called Epidiolex, which is made by GW Pharmaceuticals. After three months of treatment, 39 percent of the 23 patients had more than a 50 percent reduction in seizures, with a 32 percent median reduction.

These preliminary results support the animal studies and survey reports that CBD may be a promising treatment for treatment-resistant epilepsy, and it is generally well-tolerated in doses up to 25 milligrams per kilogram of body weight.

7. CBD May Lower Incidence of Diabetes

A 2006 study found that CBD treatment significantly reduced the incidence of diabetes in non-obese diabetic mice from an incidence of 86 percent in non-treated mice to an incidence of 30 percent in CBD-treated mice. CBD benefits also showed a significant reduction of plasma levels of pro-inflammatory cytokines. A histological examination of the pancreatic islets of the CBD-treated mice revealed significantly reduced insulitis.

In 2013, the American Journal of Medicine published a study that highlighted the impact of cannabis use on glucose, insulin and insulin resistance among U.S. adults. The study included 4,657 adult men and women from the National Health and Nutritional Examination Survey from 2005 to 2010.

Of the people in the study, 579 were current cannabis users and 1,975 were past users. The researchers found that current cannabis use was associated with 16 percent lower fasting insulin levels. They also found significant associations between cannabis use and smaller waist circumferences, a factor connected to the onset of diabetes symptoms.

8. CBD Offers Cardiovascular Health Benefits

A 2013 study published in the British Journal of Clinical Pharmacology reports that CBD protects against the vascular damage caused by a high glucose environment, inflammation or the induction of type 2 diabetes in animal models; plus, CBD proved to reduce the vascular hyperpermeability (which causes leaky gut health problems) associated with such environments.