Louisville Medicine Volume 63, Issue 3 | Page 36

SPEAK YOUR MIND If you would like to respond to an article in this issue, please submit an article or letter to the editor. Contributions may be sent to [email protected] or may be submitted online at www.glms.org. The GLMS Editorial Board reserves the right to choose what will be published. Please note that the views expressed in Doctors’ Lounge or any other article in this publication are not those of the Greater Louisville Medical Society or Louisville Medicine. GERMS ‘R US Mary G. Barry, MD Louisville Medicine Editor [email protected] I n my career so far I have fielded many questions about dietary supplements. Ordinary people who are not the vitamin-loving or the organic arugula-smoothie type want to know, what actually helps? What actually works? Are expensive ones better? At least half of all Americans take vitamins of some kind. The vitamin-loving types take lots of different pills for lots of different things and care very much about the source of the vitamin: vegan or not, organic or not, which brand, and whether oral or sublingual or liquid or sprayed. They often trust in supplements more than in pharmaceutical medications, despite the fact that the latter have randomized data lending support or rejection of use. Large randomized trials of particular vitamins are difficult to find, because of funding problems, and then difficult to interpret, because of a multiplicity of confounding variables. Manufacturers do not want to shell out millions for a study for a drug that costs $30; it’s much more attractive to spend that money on a drug they will eventually sell for $10,000 per dose. The vitaminophiles care not: they ride the swell of popular opinion, currently swinging towards coconut water, biotin, and apple cider vinegar. They take Omega-3 (despite the fact that the FDA recently said this did not help to prevent cardiovascular disease). They take mega doses of Vitamin C. They t Z