Lab Matters Summer 2019 - Page 44

APHL 2019 POSTER ABSTRACTS in devices such as needles, blood tubes, urine cups, and cryovials that are used for the collection, analysis, and storage of clinical specimens. Lot screening as the first step in the analytical process can potentially identify specific manufacturing lots of materials that have metal concentrations above targeted thresholds. Identifying unsuitable manufactured lots eliminates the likelihood of obtaining falsely elevated results due to the use of contaminated materials. Although the use of lot screening for analytical methods used for biomonitoring of metals in clinical specimens is highly recommended, numerous factors need to be considered upon implementation of a lot screening program to ensure that contamination is not introduced in the screening process by the screening laboratory. Those factors will be presented as well as a summary of the lot screening procedure used by our laboratory. Presenter: Cynthia Ward, Centers for Disease Control and Prevention, Atlanta, GA, cward@cdc.gov Innovation in Pathogen Testing: Molecular Approaches to Traditional Screening Methods that Have Arisen with the Rapidly Growing Cannabis Industry J. Bramante, H. King and M. Ward, Colorado Department of Public Health and Environment As the nascent cannabis industry grows, there is a burgeoning demand for novel approaches to pathogen detection in a variety of cannabis matrices. Notably, a need for fungal testing in cannabis products has been indicated. While fungal analysis has historically been conducted utilizing cultural methodology, there has been a recent focus on alternative, molecular-based assays for fungal identification in cannabis. In response to innovation in the industry and a desire for more rapid, highly specific approaches to testing, the Colorado Department of Public Health and Environment Laboratory Services Division Marijuana Laboratory Sciences Program has evaluated molecular-based testing platforms for the isolation and identification of Aspergillus spp. in cannabis and cannabis products. These molecular-based testing platforms serve as potential alternatives to cultural identification techniques, while also providing insight into data-supported regulation. Presenter: Julia Bramante, Colorado Department of Public Health and Environment, Denver, CO, julia.bramante@state.co.us From Meeting to Action – Leveraging Indiana’s Environmental Health System Meeting M. Hagerman, Indiana State Public Health Laboratory APHL partnered with the US Centers for Disease Control and Prevention (CDC) National Center for Environmental Health 42 LAB MATTERS Summer 2019 After the meeting, Indiana leveraged this event into action items designed to reach mothers with information on well water testing. ISDH asked that well water testing be included on immunization schedules for young children and on obstetricians’ checklist for safe pregnancy. The ISDH laboratory also worked with the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) and the Indiana section of the American Congress of Obstetricians and Gynecologists (ACOG) to alert these groups to the possible hazards of well water with a special emphasis on Arsenic, which is a naturally occurring contaminant in approximately 11% of Indiana’s well water. The ISDH laboratory is now working with the Indiana Health Commissioner to explore how the state can enlist pediatricians to promote well water testing for mothers and young children, thereby becoming a model for other states. ISDH has updated Indiana’s pregnancy mobile phone app to allow users to find recommended well water tests and testing schedules, certified laboratories and information on treatment of unsafe well water. ISDH also has implemented a regular meeting of state environmental health representatives with private well water issues on the agenda. Presenter: Mary Hagerman, Indiana State Public Health Laboratory, Indianapolis, IN, mhagerma@isdh.in.gov Science and Policy of Emerging Contaminants in Minnesota P. Moyer, S. Saravia, C. Dahle, W. Backe, J. Kelly, K. Nyquist, A. Suchomel, J. Jacobus and J. Shmool, Minnesota Department of Health Minnesota (MN) has a history of supporting environmental health (EH) activities through governmental programs, academic research, public policy, and legislation. One challenge in these broad EH efforts is ensuring that communication across sectors is adequately coordinated. This coordination is crucial to maximize existing resources and optimize requests to establish new projects. In particular, efforts in the area of contaminants of emerging concern (CEC) can be difficult to manage. Because CECs represent a broad class of contaminants, we needed to bring together representatives from the EH community in MN to help identify and prioritize this work. Within the Minnesota Department of Health (MDH), multiple programs work to address issues related to CECs including the Public Health Laboratory (PHL)1, Environmental Surveillance and Assessment (ESA)2, Chronic Disease and Environmental Epidemiology (CDEE)3, and Drinking Water Protection (DWP). The ability to coordinate this type of work both internally as well as with external partners in the CEC fields remains a challenge. In order to improve collaboration, MDH hosted a one-day meeting made possible through an Association of Public Health Laboratories grant. MDH PHL, in collaboration with ESA and CDEE, planned the full day workshop on CECs under the guidance of a professional facilitator from the Minnesota Management and Budget agency. The purpose of this meeting was to inform the attending EH professionals about the current work being done in Minnesota as well as solicit input from stakeholders to inform programs about priorities or other CEC considerations. In order for this to PublicHealthLabs @APHL APHL.org With advances in analytical technology and changes in population exposure levels (trending downward), finding suitable materials for trace metal analysis has become increasingly difficult. Our laboratory recently compiled over 16-years of lot screening data for the purpose of evaluating trends in manufacturing lot failures. A number of analytes evaluated had an increasing percentage of lots failing over time. We focused on zinc, barium, manganese, lead, beryllium, and tungsten because they had the most lot screening failures. For each element, there was a general increase in the number of lots screened per analyte for each method. A summary of this data will be provided. Environmental Hazards and Health Effects Division to provide funding for laboratories to develop and host a meeting of their environmental health system partners. Indiana was a funding recipient and hosted its meeting in October 2018 on Safe Well Water and Maternal/Child Health.