Journal of Rehabilitation Medicine 51-1CompleteIssue | Page 76

Unstable board balance test for fall identification finger along the tape measure was recorded. Subjects were then instructed to reach as far forward as possible, without taking a step, and the location of the tip of the third finger was recorded at the furthest distance reached to. The distance between the 2 marks was recorded as the functional reach distance (cm). Each subject completed 2 trials, with the maximum FRT distance obtained using in the analysis. The criterion validity, predic- tive validity, test-retest reliability, and inter-rater reliability for the FRT, for younger and older adults, has been described previously (18, 19). Timed Up and Go (TUG). The following instructions were provided to subjects: “When I say ‘go’, stand up from the chair using the armrest, walk 3 m, straight ahead, at a comfortable speed, up to the cone, turn and return to the chair, and sit down. I will record the time taken for you to complete the task, from the time you stand up from the chair to when you return to a sitting position.” Subjects completed 1 practice trial, with feedback provided as needed, and subsequently performed the actual TUG for recording. The time to complete the TUG was measured using a stopwatch, and one examiner performed all assessments. High inter- and intra-examiner reliability were previously reported for the TUG in elderly individuals (20). In addition, the TUG has concurrent validity with gait speed, the BBS, and the Barthel Index (20). Recent fall history. For the purpose of this study, a “fall” was defined as “an unexpected event in which the subject came to rest on the ground, floor or a lower level” (21). Subjects were asked to report the number of falls they had experienced over the previous year. We excluded falls resulting from extraordinary environmental factors. Statistical analysis For analysis, subjects were divided in a “faller” and “non- faller” group, according to their self-reported falls history. Demographic, personal and performance scores were compared between the 2 groups, using a χ 2 test for the categorical variable (sex) and an independent sample t-test for continuous variables. Subsequently, subjects in the faller group were matched 1:1 to subjects in the non-faller group for sex, age (± 5 years), height (± 5.9 cm for men and ± 5.1 cm for women) years, and body weight (± 7.5 kg for men and ± 6.8 kg for women), to control for the effects of these variables on test scores. The allowed ranges were defined based on known standard deviations for men and women, 70–74 years of age, published by The Ministry of Education, Science, Sports and Culture of Japan (22). For each performance test, a receiver operating characteristic (ROC) curve was calculated and the area under the curve (AUC) used to determine the accuracy of the test in differentiating fallers from non-fallers, with the AUC interpreted as follows: AUC ≥ 0.9, high accuracy; AUC between 0.7 and 0.9, moderate accuracy; and AUC between 0.5 and 0.7, low accuracy (23). The optimal cut-off value to differentiate between the 2 groups was calculated for each performance test using Youden’s index. The sensitivity, specificity, positive likelihood ratio (PLR), and negative likelihood ratio (NLR) for identified cut-off values were calculated to determine the discrimination precision for each performance test with regard to fall history, with a PLR > 5 and NLR < 0.2 indicating that the test would be clinically useful, having a high probability of correctly identifying subjects with and without history of falls (24). All analyses were performed using IBM SPSS Statistics software (version 24), with significance level p < 0.05. 73 Table I. Subjects’ characteristics Variable Age, years Sex, female/male Height, cm Weight, kg MMSE MLSI, ° FRT, cm TUG, s Recent fall Mean (SD) n 70.6 (3.6) Range (min–max) 14.0 (65.0–79.0) 23/38 161.1 (8.8) 42.0 (141.5–183.5) 60.5 (11.8) 56.5 (39.5–96.0) 28.6 (1.8) 6.0 (24.0–30.0) 8.3 (0.7) 4.9 (6.1–11.0) 30.1 (4.1) 17.0 (20.5–37.5) 8.4 (1.0) 4.3 (7.0–11.3) 9 Sex was compared between the 2 groups using a χ 2 test, with an independent t-test used for other variables. SD: standard deviation; MMSE: Mini Mental State Examination; MLSI: Medial- Lateral Stability Index, FRT: Functional Reach Test, TUG: Timed Up and Go. RESULTS Of the 66 subjects who satisfied the inclusion criteria, 2 were subsequently excluded because of a diagnosis of knee osteoarthritis, 2 because of an acute onset back pain, and 1 who had undergone total knee replacement with the previous year. The demographic and personal attributes of the 61 subjects included in the analysis, as well as their performance scores are summarized in Table I, with between-group differences on measured variables reported in Table II. The faller and non-faller groups were comparable with regard to the distribution of age and body weight, but with a greater proportion of women in the faller than non-faller group (p = 0.007); and, with a greater proportion of men, subjects in the non-faller group were taller than those in the faller group (p = 0.045). The MLSI was significantly larger for the faller than non-faller group (p = 0.040, Cohen’s d = 1.363), but with no between-group difference for the FRT (p = 0.168, Cohen’s d = 0.512) or TUG (p = 0.492, Cohen’s d = 0.254). Between-group differences on the balance perfor- mance tests, after matching between the faller and non-faller groups, are reported in Table III. During the matching process, one subject was excluded from the faller group because a matched control in the non-faller group could not be identified; data for 8 subjects in the faller group and 8 in the non-faller group were included in the analysis. Even after matching, a Table II. Comparison of variables between the faller and non- faller group (n  = 61) Faller (n  = 9) Age, years, mean (SD) Sex, female, n Height, cm, mean (SD) Weight, kg, mean (SD) MLSI, °, mean (SD) FRT, cm, mean (SD) TUG, s, mean (SD) Non-faller (n  = 52) 70.4 (3.6) 70.7 (3.6) 7 16 155.7 (8.3) 162.0 (8.6) 57.1 (14.3) 61.1 (11.3) 9.0 (1.0) 8.2 (0.5) 30.4 (4.5) 28.3 (4.0) 8.4 (0.8) 8.2 (1.0) p-value Cohen’s d 0.861 0.007 0.045 0.351 0.040 0.168 0.492 0.065 0.750 0.345 1.363 0.512 0.254 MLSI: Medial-Lateral Stability Index, FRT: Functional Reach Test, TUG: Timed Up and Go. Sex was compared between the 2 groups using a χ2 test, with an independent t-test used for other variables. J Rehabil Med 51, 2019