Journal of Rehabilitation Medicine 51-1CompleteIssue | Page 69

66 G. Müller et al. Table VI. Mean direct and indirect medical costs per year by treatment group, in EUR Direct medical costs Total costs within two years pre intervention 1 st year post intervention 2 nd year post intervention Total costs within two years post intervention Direct back pain medical costs Total costs within two years pre intervention 1 st year post intervention 2 nd year post intervention Total costs within two years post intervention Indirect medical costs Total costs within two years pre intervention BE   ST BE–ST Mean (SD)   Mean (SD) Difference % 95% CI  –4 [–692; 437] p 3,215 (5,998) 3,343 (4,329) –128 2,173 (3,355) 2,446 (4,906) –272 –11 [–644; 99] 0.151 1,799 (3,554) 3,972 (6,155) 2,289 (6,322) 4,735 (9,783) –491 –763 –21 [–917; –64] –16 [–1,467; –59] 0.024 0.034 7 1 0.658 571 (1,686)   564 (1,424) [–156; 169] 0.935 242 (1,056)   471 (252) –228 –49 [–377; –80] 0.003 242 (1,233) 485 (1,709)     253 (1,839) 723 (3,248) –10 –239 –4 [–148; 127] –33 [–451; –27] 0.883 0.027 –5 [–666; 398] 0.620 2,711 (5,362)   2,845 (5,323) –134 2 nd year post intervention Total costs within two years post intervention 1,368 (3,634)   2,563 (7,767) –119 –47 [–1,673; –716] < 0.001 1,286 (3,718) 2,654 (5,637)   1,574 (4,009)   4,137 (9,032) –288 –148 –18 [–664; 87] 0.132 –36 [–2,129; –836] < 0.001 Indirect back pain medical costs Total costs within two years pre intervention 895 (276)   967 (3,798) 72 434 (2,303)   787 (4,721) –353 –45 [–650; –56] 0.020 378 (2,788) 812 (3,737)   365 (2,516)   1,152 (5,455) 13 –340 4 [–259; 284] –30 [–754; 73] 0.926 0.107 1 st year post intervention 1 st year post intervention 2 nd year post intervention Total costs within two years post intervention 7 [–371; 228] 0.639 SD: standard deviation; CI: confidence interval; BE: back exercise; ST: standard treatment. Table VII. Difference in direct medical costs (total costs within two years post intervention) of back exercise and standard treatment Cost areas Difference % 95% CI Drugs Therapeutics Outpatient Hospital Sick pay Rehabilitation Back exercise Total –207 –36 –66 –463 –431 –28 467 –763 –22 –16 –5 –36 –53 –29 97 –16 [–480; 66] 0.318 [–75; 3] 0.069 [–177; 57] 0.248 [–855; –71] 0.021 [–693; –169] 0.001 [–74; 18] 0.235 [443; 492] < 0.001 [–1,467; –59] 0.034 effects are realized simultaneously with cost savings. Exercising is cost-effective (p < 0.05) at a maximum willingness to pay of 4,370 EUR at grade 3 GCPS, 7,500 EUR at grade 2, and 19,300 EUR at grade 1 (Table XI). MWTP values for the individual GCPS grades were determined by iterations. p CI: confidence interval. Table VIII. Back pain and functional impairments during the last 6 months (pre intervention = t0, 1 st year post intervention = t2, 2 nd year post intervention = t4) BE   ST   BE-ST Mean (SD)   Mean (SD)   Difference 6.9 (2.0)   6.4 (2.4)   2 nd year post intervention 4.8 (2.4)   5.7 (2.6)   –0.9 –15.9 [–1.2; –0.6] < 0.001 4.5 (2.4)   5.5 (2.6)   –1.0 –17.8 [–1.3; –0.6] < 0.001 Mean back pain  Within six months pre 5.1 (2.0)   4.9 (2.3)   2 nd year post intervention 3.4 (2.0)   4.4 (2.4)   –1.0 –23.3 [–1.3; –0.8] < 0.001 3.2 (2.1)   4.1 (2.3)   –0.9 –21.8 [–1.2; –0.6] < 0.001 Impairment of daily activities  Within six months pre intervention 3.8 (2.3)   3.7 (2.6)   2.3 (2.2)   3.3 (2.6)   –1.0 –30.5 [–1.3; –0.7] < 0.001 2.2 (2.2)   3.0 (2.5)   –0.8 –27.1 [–1.1; –0.5] < 0.001 Severest back pain Within six months pre intervention 1 st year post intervention 1 st year post intervention 1 st year post intervention 2 nd year post intervention Days with pain Within six months pre intervention 0.1 0.1 95% CI 8.6 [0.3; 0.8] 2.7 [–0.10.3] 3.0 [–0.1; 0.3] < 0.001 0.197 0.358 86.7 (62.6)   87.6 (67.5)   –0.9 52.5 (60.7)   75.0 (67.3)   –22.5 –30.0 [–30.7; –14.3] < 0.001 2 nd year post intervention 48.9 (57.7)   68.3 (64.7)   –19.4 –28.4 [–27.5; –11.3] < 0.001 2.2 (1.0)   2.2 (1.1)   1.5 (0.9)   2.1 (1.2)   –0.5 –26.0 [–0.7; –0.4] < 0.001 1.5 (0.9)   1.9 (1.1)   –0.4 –20.0 [–0.5; –0.2] < 0.001 1 st year post intervention 2 nd year post intervention SD: standard deviation; BE: back exercise; ST: standard treatment. www.medicaljournals.se/jrm 0.0 –1.1 [–7.3; 5.4] p 1 st year post intervention Graded Chronic Pain Status  Within six months pre intervention 0.5 % 0.9 [–0.1; 0.1] 0.775 0.722