Journal of Rehabilitation Medicine 51-1CompleteIssue | Page 39

36 J. Ponsford et al. psychological history/substance abuse variables were entered, the presence of premorbid psychological is- sues was a significant predictor of symptom reporting, whereby the odds of reporting novel PCS at follow-up in participants with these issues pre-morbidly were 2.75 times than those of participants without these issues. In Model 3 where injury-related information was entered, LOC was a statistically significant pre- dictor, whereby the odds of reporting PCS at follow- up in those who had LOC recorded were 1.94 times than those for participants who did not have LOC. Furthermore, those with unclear or not recorded LOC reported novel PCS 2.52 times more than those with no LOC. In Model 4 where recollection of receiving discharge information was entered, it was found to be a statistically significant predictor. Those who did not recall receiving information at discharge reported PCS 2.65 times more than those who were unsure. However, those who recalled receiving information at discharge DISCUSSION Table IV. Results from logistic regression models investigating predictors of novel post-injury symptom reporting, controlling for initial intervention study group and accounting for clustering of responses within emergency departments OR reported PCS 2.35 times more than those who were unsure of receiving information. In the final Model (i.e. Model 5), the presence of pre-morbid psychological issues, LOC and receipt of information were statistically significant predictors. Participants reported PCS 2.99 times more if they had pre-morbid psychological issues. If they had experienced a LOC, they reported PCS 2 times more than those who had not experienced a LOC; if LOC was questionable, participants reported PCS 2.47 times more than those who had not experienced a LOC. Participants who reported they did not receive information reported PCS 2.34 times more than those who were unsure. While participants who did recall receiving information at discharge reported PCS 2 times more than those who were unsure, this did not reach statistical significance in the final model. p-value Pseudo R 2 P for Model 95% CI Model 1 a Study group Age Sex (males) 1.17 0.98 1.53 0.625 0.001 0.081 Model 2 b Study group Psychological (absent) Time post injury Illicit (absent) Alcohol (absent) 1.22 2.75 1.00 1.26 1.83 0.475 < 0.00 0.179 0.514 0.131 Model 3 a Study group GCS LOCc (No) 1.14 0.78 0.658 0.675 0.65 to 1.99 0.25 to 2.45 Questionable 2.52 0.003 1.35 to 4.67 Yes Other injuryd (Yes) 1.94 0.005 1.22 to 3.10 No 1.14 0.630 0.66 to 1.97 Undocumented 0.73 0.135 0.48 to 1.10 Model 4 a Study group 1.12 Receipt of informatione (Unsure) 0.689 0.64 to 1.98 Yes 2.35 0.015 1.18 to 4.68 No 2.65 0.001 1.52 to 4.63 Model 5 a Study group Age Psychological (absent) LOC (No) 1.31 0.99 2.99 0.333 0.085 < 0.000 0.76 to 2.27 0.98 to 1.00 1.83 to 4.89 Questionable 2.47 0.02 0.0106 0.63 to 2.17 0.97 to 0.99 0.95 to 2.47 0.71 1.68 0.99 0.63 0.83 to to to to to 0.05 < 0.000 0.03 < 0.000 0.02 0.007 0.09 0.000 2.12 4.50 1.01 2.50 4.01 < 0.000 1.56 to 3.92 Yes 2.0 Receipt of information (Unsure) 0.029 1.07 to 3.71 Yes 2.01 0.080 0.92 to 4.40 No 2.34 0.006 1.27 to 4.30 In all models, the standard error was adjusted for clustering. Intervention group was also included in all models to control for the intervention. Number of observations: a 343; b 331; cComparison group is to those who reported no loss of consciousness (LOC); dComparison group is to those who reported other injury; eComparison group is to those who were unsure of whether they had received information in the emergency department at discharge. OR: odds ratio; CI: confidence interval. www.medicaljournals.se/jrm The aims of this study were to document outcome in terms of reported PCS, return to employment/study, anxiety symptoms and health-related quality of life and identify factors associated with persistent PCS in a series of uncomplicated mTBI cases presenting to the ED and agreeing to follow-up. Whilst 63% of participants reported no persistent PCS at follow-up, 18.7% reported 3 or more symptoms at follow-up, an average of 7 months post-injury, and 12.8% met criteria for an ICD-10 diagnosis of PCS. The most common symptoms were fatigue, for- getfulness, slowed thinking and sleep disturbance, followed by lowered frus- tration tolerance, irritability, depression, headaches and dizziness. These patterns of persisting symptoms are consistent with those found in previous longitudinal studies (4–6, 22, 37). Overall, however, the rates of PCS were low compared with many previous studies and the severity of reported symptoms was generally in the mild to moderate range. Rates of return to employment or study were high, with 92.8% of those employed pre-injury still working at follow-up, but only 60% of pre-injury students studying at follow-up. This may be partly explained by some students having completed studies. Rates of anxiety symptoms were low. Consis- tent with previous studies (8, 10), there was a statistically significant association