Iron man Iron Man USA April 2017 - Page 36

E2G EAT TO GROW droplet-associated protein, or PLIN, controls fat metabolism and storage. Unfortunately, this protein coats or covers fat droplets to protect them from being broken down by the enzyme lipase. Lastly here, but distinctively, these researchers also point out that the anti-fat/anti-obesity effects of green tomato extract was also attributed to its ability to activate the AMPK pathway. AMPK—short for AMP-activated protein kinase—serves as the body’s master regulating switch that controls cellular energy balance. Based on new and emerging research, AMPK actually recali- brates innate multifaceted genetic programs that amplify signals, which prompt the body to also accelerate fat-burning activities. Additionally, a strong body of research indi- cates that AMPK, when activated, enhances fat-burning activities by decreasing the activity of acetyl-CoA carboxylase, an enzyme that plays a key role in fatty acid synthesis or formation. As a note here, the ratio of alpha-tomatine to dehydrotomatine range from 10.9 to 12.5 micrograms per gram in tomatoes and from 2.3 to 7.8 grams in the other plant tissues. Overall, researchers estimate that immature green tomatoes contain about 500 milli- grams of a-tomatidine; however, at maturity or when green tomatoes ripen, that one kilogram of fresh green tomatoes produces about 0.5 grams of tomatine. Tomato Juice And Muscle Preservation Comparably to the above findings, research- ers at Stockholm University reported that five weeks of drinking 150 milliliters (about five ounces) per day of tomato juice standard- ized with 15 milligrams of lycopene (another active ingredient in tomatoes), substantially reduced levels of 8-dihydro-2’-deoxygua- nosine (8-oxodG), a key marker of oxidative stress and muscle damage. Studies indicate that this inflammatory chemical can elevate at levels from 42 percent to 82 percent above normal during periods of an intense workout. Amazingly, these researchers discovered that after five weeks at the dose ranges cited above, that the activity of 8-oxodG was barely detectable. From all indications, tomato juice appears to turn off inflammatory signals that inhibit muscle recovery and accelerates muscle fatigue. Conversely, researchers at the Catholic University School of Medicine in Rome discovered that the compound found in tomato’s lycopene down-regulates signals transmitted by well-known internal pathways that amplify inflammatory responses known as nuclear factor-kB (NF-kB), activated pro- tein-1 (AP-1), and mitogen-activated protein kinase (MAPK). 34 april 2017 | ironmanmagazine.com