Humanized Mouse Model Market Research Report and Forecast up to 2025 Humanized Mouse Model Market - Global Industry Ana

Humanized Mouse Model Market - Global
Industry Analysis, Size, Share, Growth, Trends,
and Forecast 2017 - 2025
Humanized mouse models are used for basic research, safety assessment for large
molecule therapeutics, modeling of certain human-specific infectious diseases, and
efficacy testing of immunotherapy approaches. The human protein is expressed
while the mouse protein is suppressed in all cells and tissues. Humanized mouse
models are important tools required to conduct preclinical research, mimic human
pathological conditions, test compound efficacy, and measure its effects on human
proteins. The model requires accurate risk assessment and thorough analysis to
preserve the physiological expression and regulation of the human gene inserted
into the mouse genome. In order to determine the optimal expression and
functionality of the human protein in a mouse environment, the genes and proteins
of both, the mouse and human, are analyzed for accuracy and structure. Humanized
mouse models are used in biomedical research including cancer biology,
regenerative medicine, human hematopoiesis, infectious diseases, transplantation,
and autoimmunity. They enable better understanding of disease pathways and
ultimately improve the translational value of preclinical studies.
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mouse-model-market.html
Technological advancements, growing prevalence of cancer, research &
development activities, and the rising adoption of personalized medicines are
factors predicted to drive the global humanized mouse model market. According to
the World Health Organization, cancer is the second leading cause of death globally
and was responsible for 8.8 million deaths in 2015. Globally, nearly 1 in 6 deaths is
caused by cancer. Government investment too plays a key role in motivating the
market. On the other hand, regulations & laws formulated for ethical use of animals
and increased use of rat models may hinder the global humanized mouse model
market.
The market has been segmented by model type into the genetic and cell-based
varieties. The latter is further segmented into the PBMC, BLT, and CD34 categories.
The growing application of CD34 models is expected to trigger the demand for them
in the near future. In terms of application, the humanized mouse model market is
classified into the following groups: oncology, immunology, infectious diseases,
neuroscience, hematopoiesis, toxicology, and others. Based on end-user, the
humanized mouse model market is categorized into the following sections: contract