HPE CINV Pocket Guide 2018 | Page 3

Contents Mechanisms 5 CINV: pathophysiology and mechanisms Sandra Melville Guidelines 13 Improving adherence and clinical outcomes Alex Molassiotis Risk factors 25 Risk factors and incidence of CINV George Dranitsaris Clinical burden 33 Clinical burden of CINV Meinolf Karthaus Pharmacoeconomics 43 Economic burden of CINV Rosanna Tarricone Treatment 51 Current status and future considerations in treatment Tiene Bauters Drug–drug interactions 65 Drug-drug interactions of the main antiemetic agents Snežana Bošnjak and Sandra Vezmar Kovacevic Pharmacy 77 The role of the specialist pharmacist Carl Booth and Saul Parkinson Made possible by a contribution from Helsinn Healthcare SA. Helsinn did not have any influence on the content and all items were subject to independent peer and editorial review hospitalpharmacyeurope.com | 2018 | 3