Hooo-Hooo Volume 10, Nr 1 - Page 17

Hemochromatosis is a condition associated with a genetic defect in iron metabolism and this term should be used for the genetic condition alone. Non-genetically associated iron accumulation should be termed iron storage disease rather than secondary hemochromatosis. Iron storage disease is a well described condition in primarily captive primates. The condition is commonly seen in primates fed on an almost exclusive fruit diet where high vitamin C levels mobilize iron stores initiating the iron accumulation. Other sources include excess iron in the diet and a deficiency of tannic acid which is an important chelating agent. In light of the hepatic pathology observed in this wildebeest, nutritional imbalances are likely important contributing factors. Chronic selenium excess (selenosis) has also been associated with hepatic iron accumulation in livestock. 2016 MARCH 17