Hep C Edition.pdf | Page 4

Treating Chronic HCV – The Past Historical treatment for HCV consisted of interferon alfa administered three times a week.7 This medication caused significant side effects and less than 10% of patients went on to achieve SVR.7 Later, pegylated versions of interferon became available, allowing patients to inject once a week. Peginterferon and the addition of ribavirin significantly increased patients’ chances of viral clearance and became the standard of care for over a decade in all HCV genotypes.7 In 2011, two protease inhibito