HeMe 1 | Page 8

Student note – Serum protein levels
Total Protein 65-85 g/l
Depends on functions of the liver, kidney, multiple myeloma, metabolic errors, and
nutritional status.
Albumin - 38-51 g/l
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Elevated in :
Dehydration, shock, hemochromatosis, intravenous intake of high concentrated
albumin solutions
Decreased in:
Nephrotic syndrome, Nephrosis, Glomerulonephritis, Chronic & Acute hepatic
insufficiency, Malnutrition, Malabsorbtion, Neoplastic disease, Leukemia

Globulin – 20-36 g/l
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Elevated in: Hepatic diseases, Infectious hepatitis, cirrhosis in liver, Billiary
Cirrohosis,Sarcoidosis,Leishmanias,Plasma cell myeloma, Lymphogranuloma,
Lymphoproliferative disease,Hemochromatosis,Typus,Malaria,Lymphogranuloma
venerum.
Decreased in : Malnutrition, Congenital agammaglobulinemia,Acquired
hypogammaglobulinemia, Lymphatic leukemia.

Fibrinogen – 2-6 g/l
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Elevated in : Glomerulonephritis, Nephrosis, Infectious disease.
Decreased in : Disseminated intravascular coagulation syndrome, Accidents of
pregnancy---placental abla tion, amniotic fluid embolism, violent labor, Metastatic
carcinoma in prostrate, Meningococcal meningitis, Acute and chronic hepatic
insufficiency, Congenital Fibrinogenopenia.