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Low risk HPVs , which do not cause cancer but can cause skin warts , precisely known as condylomata acuminate , are found on or around the genitals and anus . For example , HPV types 6 and 11 cause 90 % of all genital warts . HPV types 6 and 11 also cause recurrent respiratory papillomatosis , a disease in which benign tumors grow in the air passages leading from the nose and mouth into the lungs .
High-risk HPVs - which can cause cancer . About a dozen high-risk HPV types have been identified . Two of these , HPV types 16 and 18 , are responsible for most HPV-caused cancers . On the basis of vaccines , the global market size is classified into bivalent and a quadrivalent vaccine . Both vaccines are highly effective in preventing infection with virus types 16 and 18 , which are together responsible for almost 70 % of cervical cancer cases globally . The vaccines are also highly effective in preventing precancerous cervical lesions caused by these virus types .
The quadrivalent vaccine is also highly effective in avertinganogenital warts , a common genital disease which is practically always caused by infection with HPV types 6 and 11 . Data from clinical trials and initial post - marketing surveillance conducted in several continents show both vaccines to be safe . On the basis of application , the global market size is classified into pediatric , adult , and others . Geographically , the global market size is segmented into North America , China , Europe , Japan , India , and Southeast Asia .
North America and Europe accounts for the maximum market share of the global HPV vaccines market and is expected to grow at highest CAGR during the forecast period . This is due to the governments from major countries of these regions having publicly funded HPV vaccination . The key players of the market size are Astellas Pharma Inc , CSL Limited , Emergent BioSolutions , Inc , GlaxoSmithKline , Johnson & Johnson , MedImmune , LLC , Merck & Co , Pfizer , Sanofi Pasteur , Serum Institute , and India Pvt . Ltd .
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