HeadWise Volume 3, Issue 3 | Page 15

Congenital malformation rates differ between countries but are generally around 3% of 4 million US annual live births and are the leading cause of infant mortality in the United States. About 4% of congenital malformations are caused by teratogens, agents that can cause abnormalities in the form or function of a developing fetus. Specific teratogens include infectious agents, maternal disease, physical e