ONZETRA TM Xsail TM provides FAST pain relief
Almost half of migraine sufferers experienced pain relief in 30 minutes ( 42 % vs 27 % on placebo ) and 68 % experienced pain relief in 2 hours vs 45 % on placebo .
Breath Powered ® delivery
ONZETRA is taken with a small , innovative device called Xsail . It uses your own breath to deliver migraine medicine directly to the back of your nose , an area with the potential for fast absorption .
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Important Safety Information
What is ONZETRA TM Xsail TM ( sumatriptan nasal powder ) used for ? ONZETRA Xsail is a prescription medication approved for the acute treatment of migraine , with or without aura in adults . ONZETRA Xsail is used for people who have been told by a healthcare provider that they have migraine headaches . ONZETRA Xsail is not for the prevention of migraines or for other types of headaches , including cluster headache .
What important information should I know about ONZETRA Xsail ? ONZETRA Xsail may cause serious side effects , including :
• Heart attack and other heart problems , which may lead to death . Stop using ONZETRA Xsail and get emergency medical help right away if you have any symptoms of a heart attack like shortness of breath or tightness , pain , pressure , or heaviness in your chest , throat , neck , or jaw that is severe or does not go away
• Changes in color or sensation in your fingers and toes ( Raynaud ’ s syndrome )
• Stomach and intestinal problems ( gastrointestinal and colonic ischemic events )
• Problems with blood circulation to your legs and feet ( peripheral vascular ischemia )
• Serious allergic reactions ( symptoms include hives ; tongue , mouth , lip , or throat swelling ; problems breathing )
• Medication overuse headaches . Some people who use ONZETRA Xsail too many times may have worse headaches . If your headaches get worse your doctor may decide to stop your treatment with ONZETRA Xsail
• Serotonin syndrome , a rare but serious problem that can happen in people using ONZETRA Xsail , especially if ONZETRA Xsail is used with antidepressant medicines called SSRIs , SNRIs , or TCAs . Call your doctor right away if you have any of the following symptoms of serotonin syndrome : mental changes such as seeing things that are not there ( hallucinations ), agitation , or coma ; fast heartbeat ; changes in blood pressure ; high body temperature ; tight muscles ; trouble walking ; or nausea , vomiting , or diarrhea
• Seizures . Seizures have happened in people taking sumatriptan who have never had seizures before
The most common side effects of ONZETRA Xsail are abnormal taste , discomfort of your nose or throat , runny nose , and stuffy nose . This is not a complete list of side effects . Tell your doctor about any side effect that bothers you or does not go away .
30 HeadWise ® | Volume 6 , Issue 2 • 2016