HeadWise HeadWise: Volume 4, Issue 4 - Page 15

For adults with Chronic Migraine, 15 or more headache days a month, each lasting 4 hours or more, FOR ADULTS WITH CHRONIC MIGRAINE BOTOX® is the first and only preventive treatment proven to reduce headache days every month. injection BOTOX® is the only FDA-approved, preventive treatment that is injected by a doctor every 3 months for people with Chronic Migraine. BOTOX® prevents up to 9 headache days a month, versus up to 7 days for placebo. BOTOX® is not approved for adults with migraine who have 14 or fewer headache days a month. Find a headache specialist near you at BotoxChronicMigraine.com BOTOX® is a prescription medicine that is injected to prevent headaches in adults with Chronic Migraine who have 15 or more days each month with headache lasting 4 or more hours each day in people 18 years or older. It is not known whether BOTOX® is safe or effective to prevent headaches in patients with migraine who have 14 or fewer headache days each month (episodic migraine). IMPORTANT SAFETY INFORMATION BOTOX® may cause serious side effects that can be life threatening. Call your doctor or get medical help right away if you have any of these problems any time (hours to weeks) after injection of BOTOX®: • Problems swallowing, speaking, or breathing, due to weakening of associated muscles, can be severe and result in loss of life. You are at the highest risk if these problems are pre-existing before injection. Swallowing problems may last for several months. • Spread of toxin effects. The effect of botulinum toxin may affect areas away from the injection site and cause serious symptoms including: loss of strength and all-over muscle weakness, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice (dysphonia), trouble saying words clearly (dysarthria), loss of bladder control, trouble breathing, trouble swallowing. If this happens, do not drive a car, operate machinery, or do other dangerous activities. There has not been a confirmed serious case of spread of toxin effect away from the injection site when BOTOX® has been used at the recommended dose to treat Chronic Migraine. Please see additional Important Safety Information on adjacent page. © 2014 Allergan, Inc., Irvine, CA 92612. ® marks owned by Allergan, Inc. Dysport is a registered trademark of Ipsen Biopharm Limited Company. Myobloc is a registered trademark of Solstice Neurosciences, Inc. Xeomin is a registered trademark of Merz Pharma GmbH & Co KGaA. APC43DI14 www.headaches.org | National Headache Foundation 15