HAPI Guide HAPIguide FALL 2017 | Page 9

HEALTH ing inhalation for issues that range from migraines to mental health. It’s really helpful for someone who has a sudden acute exacerbation due to the situation they’re in, like with PTSD. It’s not meant to be used for everything, so my advice to patients predominately is that the best way is to ingest it, because it’s more like a medication. You’ll have a slow rise in the effects, and it’ll plateau for a good six to eight hours, so you have good relief. Unlike for migraines and mental health, with chronic pain you don’t want to have like a yo-yo effect, because if you inhale, you’ll have sudden relief of your symptoms, usually in a matter of minutes, but the peak effects are at about 20 to 30 minutes, and most of the effects are gone by an hour and a half. For people that are chronic pain sufferers, they really need much better and long lasting relief. Can cannabis help chronic pain without get- ting you high? Yes. My company has actually created organic CBD products from hemp that do just that. Cannabidi- ol, or CBD, is a great anti-inflammatory agent and great for pain. It is legal in all 50 states, unlike THC or cannabis, which is allowed in only 29 states. You may even find CBD oil in convenience stores that people can use in a vaporizer. Your body actually has its own endogenous can- nabinoid system. There are two specific recep- tors that researchers have found that create the differences in terms of therapy between THC and CBD. THC has a greater affinity for the CB-1 recep- 9 | HAPI Guide tor, which is present throughout the central and peripheral nervous system. If THC binds to the CB-1 receptor, it actually increases the likelihood of neurotransmission between neurons, whereas CBD or cannabidiol has a greater affinity for CB-2 receptors. CB-2 receptors are throughout your im- mune system, both in B cells and T cells. CBD works through multiple pathways; for example, if there are cells that are growing at a much faster rate than needed, it will actually tell them to shut themselves down and lead to cell death, or apoptosis. CBD also will decrease the production of agents that lead to inflammation, like cytokines, as well as decrease the production of growth factors. There are a lot of endogenous growth factors that are increased if someone has cancer, so THC and CBD have really very different effects on the body, but CBD is a great way to deal with chronic pain. I was interested in creating CBD products from hemp, and we started that about a year and a half ago. We actually went to multiple processors in Colorado, Oregon, visited their sites, wanted to make sure that they did best practices. We work with two processors in Colorado and one in Ore- gon, everything is done organically, all the culti- vators and processors are certified. We actually get testing of the oil that we get twice, once with