Golden Box Book Publishing Asthma Relief with Grandmas Remedies | Page 15

The Possible Causes of Asthma
Genetic factors
The genetic trait, CD14 single nucleotide polymorphism (SNP) C-
159T, and exposure to endotoxin (a bacterial product) are a well-
replicated example of a genetic-environment interaction that is
associated with asthma. Endotoxin exposure varies from person to
person and can come from several environmental sources.
Researchers have found that risk for asthma changes based on a
person's genotype at CD14 C-159T and the level of endotoxin
exposure. The interaction is complex and not fully understood.
Research suggests that some genetic variants may only cause asthma
when they are combined with specific environmental exposures, and
otherwise may not be risk factors for asthma.
Environmental factors
Many environmental risk factors have been associated with asthma
development and morbidity in children. Recent studies show a
relationship between exposure to air pollutants and childhood
asthma. This research finds that both the occurrence of the disease
and exacerbation of childhood asthma are affected by outdoor air
pollutants. High levels of endotoxin exposure may contribute to
asthma risk.
Viral respiratory infections
Viral infections are not only one of the leading triggers of an
exacerbation but may increase one's risk of developing asthma,
especially in young children. Respiratory infections such as
rhinovirus, Chlamydia pneumoniae, and Bordetella pertussis are
correlated with asthma exacerbations.
Psychological stress
Stress has long been suspected of being an asthma trigger, but only
in recent decades has convincing scientific evidence come forth.
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