FreedomEdge Patient Guide | Page 2

WhySub-q? A subcutaneous (sub-q) infusion delivers medication through a thin needle to the fatty tissue just under the skin. See page 11 for common places to infuse. Compared to IV, sub-q means smaller needles and more personal choice over when to infuse. It eliminates the need for vein punctures. Studies show sub-q may reduce adverse reactions such as severe headache, nausea, and vomiting. Many healthcare providers and patients prefer sub-q immunoglobulin (SCIg) over intravenous delivery (IVIg). SCIg IVIg vs. Can be administered daily to monthly, as determined by your provider Administered once every 3-4 weeks No venous access required Venous access required Can be self-infused at home after brief training Usually administered by trained healthcare personnel Can be done anywhere at patient’s convenience Usually administered at healthcare office/hospital Subcutaneous slows down the rate that medication enters the bloodstream. Combined with more frequent delivery, this provides more consistent and stable blood levels, decreases side effects and improves overall quality of life. SCIg IVIg Ig Levels (g/L) 18 12 6 0 14 Days 28