Fibromyalgia & Chronic Pain LIFE Winter 2014, Issue 10 | Page 9

Professional Medical Advice ELECTRICAL. The second method is electrical. The brain and spinal cord are centers of heat production. Heat is generated as the neurons build up electrical charge, then rapidly discharge at the cell surface. This constant charge separation and combination demands an enormous amount of energy and releases large amounts of heat. CHEMICAL. The third method is chemical. Research into the problem of chemically created body heat has been sporadic with little government funding but progress is being made. The sub cellular organelles called mitochondria are the sites of ATP production for all cells. ATP (AdenosineTriPhosphate) and related molecules are the intracellular currency. Need to repair DNA? Then you shall pay with several ATP. Need to distribute a hormone signal within the cell? You shall pay with ATP. ATP is the biochemical most easily and efficiently translated into work energy by thousands of enzymes present within most cells. Mitochondria are quite efficient at producing ATP. About 90% of the possible energy from foods such as citrate, succinate and malate is transformed into potential energy as ATP by the mitochondria. The citrate, succinate and malate are used up with oxygen in the creation of water and carbon dioxide (chemical combustion). Cold blooded animals like snakes and lizards use this 90% efficiency extremely well because they don’t have to spend all of their time finding food. A lizard only needs to eat a large meal about once a week, giving him much more time for lying on warm rocks to enjoy the sun. “If you have low magnesium and low thyroid function, you will have trouble maintaining homeothermia or the perfect number of 98.6º.” Warm-blooded animals, on the other hand such as humans, create heat by burning citrate, succinate and malate but do not always generate ATP. Biochemically, this is called uncoupling the mitochondria; a short way of stating that chemical combustion occurs in the mitochondria without production of ATP. Another term used is thermogenesis or heat creation. All physical scientists will then ask, “How much heat is liberated?” since you cannot have chemical combustion without liberating heat. The answer is “enough to heat mammals from room temperature of 75 to 98.6ºF..” Mammals have the innate ability to hormonally control the method for heat production via the mitochondria via the uncoupling protein (UCP1) in fat tissues. UCP1 is controlled by both the thyroid and