Eversight Illinois Vision Spring 2017 SpringVision_IL_19Apr17_FNL | Page 10

INNOVATION ­ “We have to continue evolving and improving our treatments and can never stop at what we have.” Dr. Shahzad Mian, University of Michigan Kellogg Eye Center corneal surgeon and Eversight Medical Director Dr. Mian’s words couldn’t ring more true. What we know today about treating blindness was made possible by the people before us who believed there was a better way. At the core of our mission, Eversight is dedicated to advancing new treatments through technology, partnerships and clinical practices that will make sight restoration better than ever before. Changing climate Excellence in action Eversight provides tissue for more than 2,500 transplant patients outside the United States every year, and with each delivery there are many logistical challenges to overcome, particularly climate. International shipments are often exposed to extreme temperature fluctuations, from near-zero conditions in the United States to desert regions like Abu Dhabi where the temperature can average nearly 100 degrees Fahrenheit. But during this long journey, the packaging must maintain a stable internal environment to keep the tissue safe. Two years of hard work paid off for Lauren Johnson, Eversight Tissue Processing Services Manager, and Dr. Parag Majmudar of Chicago Cornea Consultants, after investigating parameters affecting endothelial cell health for a tissue-staining procedure popular with both surgeons and eye banks. One tiny device, called an electronic data logger, is changing the way Eversight delivers tissue abroad. The logger, no larger than a USB drive, is placed inside the tissue cooler and collects temperature data throughout the shipping process. Once the package arrives at its destination, a surgeon can view the recorded data and verify safe shipping conditions. The cornea is vulnerable to damage if the dye is applied too long, especially for procedures like DMEK in which the tissue is no thicker than a human hair. If not dyed long enough, surgeons may have difficulty positioning the tissue properly. Both factors can increase the incidence of transplant complications and even rejection. Early results from the device led Eversight to adopt new packaging that can maintain a constant internal temperature for 72 hours in any climate—an important factor when sending tissue thousands of miles around the globe. “The data logger has been an incredible tool for upholding the highest standards in safety and quality of the tissue we provide for transplants,” said Erik Hellier, Director of International Clinical Services. “Technology like this aids us in giving sight to anyone in the world.” Using grant funding provided by the Eye Bank Association of America, the pair discovered the optimal time to stain the cornea with trypan blue dye, a process commonly used to help surgeons visualize tissue during surgery. “Finding the right balance to satisfy surgeon needs duri