Ocular
SAEVA Neosporin
Procedures Local therapy for all ocular problems
and Policies | EQUINE
Conjunctivitis Fusidic acid Mild corneal ulceration Consider artificial tears/
plasma
Gentamicin Gentamicin Most cases trauma
Ciprofloxacin
Ciprofloxacin Consider keratomycosis
Severe corneal ulceration
Melting corneal ulceration
Antibiotic use policy
Miscellaneous
rder to comply with good antimicrobial stewardship
gely rests on a document produced by the New Zealand Veterinary
Endocarditis
Penicillin & Gentamicin
Trimethoprim &
ion-it most closely resembles the South African situation.
Sulphadiazine &
for us by Dr Pia Randleff-Rasmussen- Drakenstein Veterinary Clinic Rifampicion
Fluoroquinolones
Core Principles
Trimethoprim &
Penicillin & Gentamicin
Neutropenia >1 & <2.4x10°/;
Sulphadiazine
Pyrexia of unknown origin
the impacts of antimicrobial use on human and animal health is made by all
Penicillin & Gentamicin
Penicillin & Gentamicin
Neutropenia <1x x 10°/l
or administering antimicrobial agents.
& Metronidazole
nditions that could require antimicrobial therapy is a key focus of veterinary
Neonate <3 Weeks
antimicrobial agents only as required to maintain their health and welfare.
Neonatal pneumonia
Ceftiofur
Penicillin &
ng the number of animals given antimicrobial agents are employed where this
Gentamicin/Amikacin
mise animal health or welfare.
Septice arthritis / synovitis
Penicillin &
Trimethoprim &
bial agents are used, dose rates and regimens are designed to improve efficacy
Gentamicin/Amikacin
Sulphadiazine
ment.
Oxytetracycline or
ents considered more important in human medicine are not used as first line Doxycycline
Patent urachus
Not indicated
Oxytetracycline or
e only employed when use is likely to deliver superior outcomes.
Doxycycline
Unbilical infection
Trimethoprim &
Peniciilin &
Sulphdiazine
Gentamicin/Amikacin
SEPSIS
Ceftiofur high doses (5-
Penicillin &
10 mg/g TID)
Gentamicin/Amikacin
SEVERE SEPSIS
Ceftiofur &
Pencillin & Gentamicin &
Gentamicin/Amikacin
Metronidazole
Meningitis
Ceftiofur
Penicillin &
Gentamicin/Amikacin
Prophylaxis
Pre-Operative
Post-Operative
Blood and urine cu ltures before therapy
Blood cultures at peak fever BEFORE Abs
Avoid antimicrobials where viral cause, e.g.
equine corona virus, is suspected
*Clinically important but justified in neonate due
to high mortality
Consider source (lungs, GI, umbilicus), if
latrogenic, consider MRSA (Macrolides /
Fluoroquinolones)
Abs not indicated unless sepsis is involved.
Avoid dehydration at all costs
Infection + 2 of: tachycardia, abnormal Temp,
Resp. WBC
Defined as sepsis with organ dysfunction,
hypoperfusion, or hypotension
No BBB in meningitis
Consider source
Duration of post-operative treatment
Clean surgery Penicillin 24 hours, i.e. one dose
Contaminated surgery Pencillin & Gentamicin Penicillin & Gentamicin 5 days
High risk surgery Penicillin & Gentamicin Penicillin & Gentamicin 10 days, then reassess.
Consider TMP-S if longer treatment required
• Volume 20 Issue 2 | July 2018 •
45