Equine Health Update EHU Vol 20 Issue 02 - Page 43

der to comply with good antimicrobial stewardship Notes Upper Respiratory Tract Disease ely rests on a document produced by the New Zealand Veterinary on-it most closely resembles the South African situation. Strangles Formed abscess Not indicated Penicillin or us by Dr Pia Randleff-Rasmussen- Drakenstein Veterinary Clinic (uncomplicated strangles) Primary Sinusitis Trimethoprim & Sulphadiazine Guttural pouch empyena / Penicillin he impacts of antimicrobial use on human and animal health is made by all Oxytetracycline or chondroids Doxycycline r administering antimicrobial agents. Lower Respiratory Tract Disease ditions that could require antimicrobial therapy is a key focus of veterinary Core Principles Penicillin Primary pneumonia Penicillin & Gentamicin Oxytetracycline or ntimicrobial agents only as required to maintain their health and welfare. Doxycycline g the number of animals given antimicrobial agents are employed where this se animal health or welfare. .RAO/COPD (Equine asthma) Not Indicated Not indicated al agents are used, dose rates and regimens are designed to improve efficacy ment. Rhodococcus pneumonia Azithromycin / Rifampin & Doxycycline nts considered more important in human medicine are not used as first line Clarithromycin + (10mg/kg BID PO) Rifampin only employed when use is likely to deliver superior outcomes. Wounds Contaminated wounds with synovial sepsis Contaminated wound with open fracture Penicillin & Gentamicin Contaminated wounds (non- complicated) Skin / Hoof Cellulitis TMS is contraindicated since it is inactivated in the presence of pus. NB secondary sinusitis: see GI disease. TMPS inactivated by pus, so must have lavage as well. Strep equi most commonly implicated Extremely uncommon Affected animals systematically ill Metronidazole if anaerobes suspected Secondary pneumonia more common than primary Only if large or multiple abscess and/or sick foal Not indicated Oxytetracycline/ Doxycycline IVRP (adjust aminoglycoside dose if adding via IVRP) Not indicated Synovial debridement and lavage most often indicated Metronidazole if anaerobes suspected Fracture care is more important than antimicrobial therapy Debridement and drainage is far more important than antibiosis