< RESULTS >
Results from experiment 1 are presented in Figures 1-2 below . Results from experiment 2 are presented in Figure 3 . In experiment 1 , Purina ® Outlast ™ gastric supplement buffered the simulated gastric environment to a higher level than all other measured supplements . Additionally , the buffering capacity of Purina ® Outlast ™ gastric supplement was higher than that of the other supplements . In experiment 2 , Purina ® Outlast ™ gastric supplement buffered the simulated gastric environment more quickly than the other supplements tested reaching 78.4 % of its maximum buffering capacity at 2 minutes .
< IMPLICATIONS >
The continual presence of gastric acid in the equine stomach , even during times when the horse is not eating can be considered a major factor in the development of gastric ulcers . Data from this study indicate that Purina ® Outlast ™ gastric supplement buffered the simulated gastric environment to a higher level than other products tested , and does so quicker and to a greater extent than the other supplements tested , including alfalfa . For horses experiencing stressors such as trailering , exercising , confinement , weaning and others Purina ® Outlast ™ gastric supplement may have the ability to buffer the gastric acid in the stomach , producing a more favorable gastric environment and reducing the potential for gastric ulceration .
FIGURE 1 |
In vitro buffering ability of Purina ® Outlast ™ Gastric Supplement compared to similar supplements . |
FIGURE 2 |
In vitro buffering ability of Purina ® Outlast ™ Gastric Supplement over time compared to similar supplements . |
in vitro pH |
8 7 6 5 4 3 2 1 0 |
* |
* |
* * |
∞ |
Max pH - Min pH / time ( min ) to reach max pH |
1.4 1.2 1 0.8 0.6 0.4 0.2 0 |
0 |
30 |
60 90 120 150 180 210 240 270 300 330 360 |
|
|
Time ( minutes ) |
OUTLAST a |
ALFALFA b |
COMP 1 b |
COMP 2 b |
COMP 3 a |
COMP 4 b |
COMP 5 b |
COMP 6 b |
COMP 7 LOW b |
COMP 7 HIGH a |
Differing superscripts indicate differences based on a dummy regression at P < 0.05 ( R 2 = 0.92 ) * Indicates differences between Purina ® Outlast™ and other treatments at P < 0.05 ∞ Indicates differences between Purina ® Outlast™ and other treatments at P < 0.10
|
OUTLAST a
ALFALFA b
COMP 1 b
COMP 2 b
COMP 3 b
COMP 4 b
COMP 5 b
Differing superscripts indicate differences at P < 0.05
|
COMP 6 b |
COMP 7 LOW b |
COMP 7 HIGH a , b |
FIGURE 3
In vitro Buffering Speed of Purina ® Outlast ™ Gastric Supplement Compared to Similar Supplements . **
in vitro pH
4 3 2 1 0
0 2 4 6 8 10 Time ( minutes )
OUTLAST a ALFALFA b COMP 3 b COMP 6 b COMP 7 HIGH b
** Comp 3 , 6 , 7 ( high ) were chosen for comparison as they were the top performers in HR 246 . To review the full data set , see the research review titled “ Purina ® Outlast™ Gastric Supplement Optimized pH in a Simulated Gastric Environment More Effectively than Other Similar Products ” Differing superscripts indicate differences based on a dummy regression at P < 0.05 ( R 2 = 0.92 ) * Indicates differences between Purina ® Outlast™ and other treatments at P < 0.05 ∞ Indicates differences between Purina ® Outlast™ and other treatments at P < 0.10
< AVAILABLE UPON REQUEST > Contact your local Purina representative if you would like more information about this study .
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