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What’s really behind your patient’s hyponatremia? Excess vasopressin may be complicating your patient’s treatment Elevated vasopressin levels can cause abnormal water retention, leading to hyponatremia (serum sodium <135 mEq/L).1,2 Hyponatremia may increase mortality risk and length of hospital stay and adversely affect outcomes for patients with various medical conditions.1,3 Pull back the curtain on hyponatremia Na References: 1. Verbalis JG, Goldsmith SR, Greenberg A, et al. Diagnosis, evaluation, and treatment of hyponatremia: expert panel recommendations. Am J Med. 2013;126(10 suppl 1):S1-S42. 2. Douglas I. Hyponatremia: why it matters, how it presents, how we can manage it. Cleve Clin J Med. 2006;73(suppl 3):S4-S12. 3. Shorr AF, Tabak YP, Johannes RS, Gupta V, Saltzberg MT, Costanzo MR. Burden of sodium abnormalities in patients hospitalized for heart failure. Congest Heart Fail. 2011;17(1):1-7. ©2014 Otsuka America Pharmaceutical, Inc. SAMS14CDNY6633_Unbranded_Journal_Ads_Single_Page_r9_FSU.indd 1 November 2014 07US14EUP0478 3/18/15 12:20 PM