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CLINICAL NEWS American College of Cardiology Extended Learning Cardiorespiratory Fitness as a Vital Sign Yes, but how? I s weight loss the optimal target for obesityrelated cardiovascular disease risk reduction? Probably not. That’s based on the life’s work of several pioneers in this field, including Robert Ross, PhD, a professor of exercise physiology at the School of Kinesiology and Health Studies, Queen’s University, Kingston, Ontario. Sure, weight loss is associated with substantial reduction in obesity-related CVD risk and certainly is a desired outcome. However, Dr. Ross and others have established that increasing physical activity is associated with marked reduction in waist circumference, visceral fat, and cardiometabolic risk factors, concurrent with an increase in cardiorespiratory fitness (CRF)—despite minimal or no change in body weight. Consider the 2004 paper Dr. Ross published with Steven N. Blair, PhD, a professor at the Arnold School of Public Health, University of South Carolina, Columbia, SC, and another pioneer in exercise and CRF.1 Cardiorespiratory fitness is associated with lower abdominal fat independent of body mass index (BMI). Specifically, in comparing men with high CRF (n = 169) with men showing low CRF (n = 124), they demonstrated that for a given BMI, men in the high CRF group had significantly lower waist circumference (p < 0.001) as well as lower total abdominal tissue (p < 0.001), visceral adipose tissue (p < 0.001), and abdominal subcutaneous adipose tissue (p < 0.001) compared with men in the low CRF group. Subsequently, a much larger study was performed providing compelling evidence that waste circumference explains both diabetes and CVD risk beyond that explained by BMI alone. The IDEA study (International Day for Evaluation of Abdominal Obesity) involved 6,407 randomly chosen primary care physicians in 63 countries, who evaluated 168,159 patients ages 18 to 80 years.2 To listen to the There was a graded interview with Robert increase in the frequency of Ross, PhD, on the topic of implementing CVD and diabetes mellitus CRF measurement in with both BMI and waist clinical practice, visit circumference but there was a the CSWN YouTube channel channel by stronger relationship for waist scanning the QR code circumference than for BMI below. The interview across regions for both sexes. was conducted by Christopher M. Shortly thereafter, Ross and Kramer, MD. colleagues demonstrated that waist circumference predicts diabetes risk beyond BMI and other commonly measured cardiometabolic risk factors, such as smoking, dyslipidemia and blood pressure.3 26 CardioSource WorldNews The data are summarized in a paper published by Dr. Ross and Peter M Janiszewski, MSc.4 Together, the evidence underscored the importance of waist circumference as a routine measure in clinical practice that should be a primary treatment target for strategies designed to reduce obesity-related CVD risk. Indeed, Dr. Ross and others think that exercise should be viewed as a cost-effective medication for all patients with or at-risk for CVD. HOW DO YOU THAT? It’s not easy—as most clinicians probably try this approach regularly (usually feeling as if their efforts just don’t work)—but there are suggestions that Dr. Ross and colleagues promote5 that can be highly beneficial. Motivating exercise in the physician office or clinical environment: If physicians, physical therapists, dietitians, and other health professionals all consistently assess and promote physical activity as a routine component of every clinical encounter, they note “it is likely that we would start to see changes in patient self-reported physical activity.” Think realistically: Dr. Ross noted recently, “The clinical reality for most in patient care disciplines is that our patients are mostly sedentary and have been that way for their entire adult lives. The expectation that they will suddenly become someone who performs 30 minutes of exercise on most days of the week is simply unrealistic. Key to promoting cardiorespiratory fitness in the clinical setting is the use of a physical activity vital sign in which every patient’s exercise habits are assessed and recorded in their medical record. Those not meeting the guideline-recommended 150 minutes per week of moderate intensity physical activity should be encouraged to increase their physical activity levels with a proper exercise prescription. According to Dr. Ross: “If you maintain that 150 minutes of activity most weeks, you will improve your cardiorespiratory fitness and you will reduce morbidity and mortality substantially. They write, “We can improve compliance by assessing our patient’s barriers to being more active and employing new and evolving technology like accelerometers and smart phones applications, along with various websites and programs that have proven efficacy.”5 Manage realistically: Help patients access and manage their exercise and physical activity; you can only manage what you measure. Encourage patients to keep track of their adherence to exercise and track their daily activity. This can be done on paper, or increasingly, with a myriad of digital devices and smart phone applications. Practice what you preach: “Each and every health care professional involved with helping patients manage chronic disease conditions that may benefit from increased adherence to exercise and physical activity must be aware that our patients often ask what we do. If we do not adhere to exercise therapies, then they may be less likely to themselves,” he emphasized. According to Dr. Ross, physical inactivity is the major public health problem of our time. While obesity is most often publicized, its adverse effects on health are largely mitigated by engaging in regular physical activity. Physicians cannot do it alone: Everyone on the health care team, from the front desk receptionist to the medical assistant, nursing staff, dietitians, physical therapists, etc., needs to be on the same page: actively promoting regular physical activity as a key to improved health outcomes. Likewise, the expanded use of technology to track activity can help support the achievement of step goals. According to Dr. Ross, ultimately, to succeed, “we need to leverage all the tools in our toolbox and continue to investigate and add new tools in our efforts to help our patients, our families, and our communities move more.” ■ REFERENCES: 1. Wong SL, Katzmarzyk P, Nichaman MZ, et al. Med Sci Sports Exerc. 2004;36:286-91. 2. Balkau B, Deanfield JE, Despres JP, et al. Circulation. 2007;116:1942-51. 3. Janiszewski PM, Janssen I, Ross R. Diabetes Care. 2007;30:3105-9. 4. Ross R, Janiszewski PM. Can J Card iol. 2008;24(Suppl D):25D-31D. 5. Sallis R, Franklin B, Joy L, et al. Prog Cardiovasc Dis. 2015;57:375-86. Take-aways • The connection between physical activity and health has been clearly established, and exercise should be viewed as a cost-effective medication for all patients with or at risk for CVD. • Physicians cannot do it alone but must be joined by the entire team—from receptionist to all other staff and associates who meet patients—who should be on the same page promoting physical activity. • The expanded use of technology to track a patient’s activity can help support the achievement of step goals. • Ultimately clinicians will need to leverage all the tools in their toolbox and continue to investigate and add new tools so that patients, their families, and our communities move more. June 2016