CardioSource WorldNews September 2015 | Page 37
A pulmonary embolism may
lead to an unfamiliar, serious
consequence.
1, 2
*
As many as 1 out of every 25 of your previously
treated PE patients (>3 months of anticoagulation3)
may develop chronic thromboembolic pulmonary
hypertension, or CTEPH.1,4*
A ventilation-perfusion (V/Q) scan can rule out
CTEPH in PE patients with chronic symptoms5
after >3 months of anticoagulation.3
References:
1. Fedullo P, Kerr KM, Kim NH, Auger WR. Chronic
thromboembolic pulmonary hypertension. Am J
Respir Crit Care Med. 2011;183(12):1605-1613.
2. Pengo V, Lensing AWA, Prins MH, et al.
Incidence of chronic thromboembolic pulmonary
hypertension after pulmonary embolism.
N Engl J Med. 2004;350(22):2257-2264.
3. Wilkens H, Lang I, Behr J, et al. Chronic
thromboembolic pulmonary hypertension (CTEPH):
updated recommendations of the Cologne
Consensus Conference 2011. Int J Cardiol.
2011;154S:S54-S60.
4. Tapson VF, Humbert M. Incidence and
prevalence of chronic thromboembolic
pulmonary hypertension: from acute to chronic
pulmonary embolism. Proc Am Thorac Soc.
2006;3(7):564-567.
5. Kim NH, Delacroix M, Jenkins DP, et al.
Chronic thromboembolic pulmonary hypertension.
J Am Coll Cardiol. 2013;62(suppl D):D92-D99.
If you know what to look for, a V/Q scan
makes it relatively easy to spot.5
*Based on a study with 223 patients in which 3.8% were diagnosed with CTEPH
within 2 years of their first episode of pulmonary embolism with or without prior
deep-vein thrombosis (95% CI, 1.1 to 6.5). CTEPH did not develop after two years
in any of the 132 remaining patients with more than 2 years of follow up.
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