Beyond MAY 2017 Issue - The Power Of Foods BEYOND_ThePowerOfFood issue_050417 | Page 9

Bone health is dependent on a constant supply of micronutrients for maintenance and repair. Instead of adopting a singlenutrient, unbalanced approach to supplementation, BeyondBasix utilizes an array of complementary, well-researched nutrients in its Fx4 Foundation Bone formulas to build and maintain bone over time. All BeyondBasix Formulas Meet or Exceed cGMP Quality Standards Let’s take a closer look on what makes up Fx4: Bone Builder and the research behind it. Silicon as Choline-Stabilized Orthosilicic Acid (ch-OSA®) Fx4 Foundation Bone formulas feature ch-OSA, a patented, stabilized, readily absorbed, bioactive form of silicon called orthosilicic acid. Decades of research suggest that there is a strong, positive association between dietary silicon and bone mineral density (BMD). The mechanisms of action appear to be silicon’s support of collagen synthesis and stabilization, extracellular matrix mineralization, and connective tissue CLINICAL APPLICATIONS integrity. In cell-line studies, orthosilicic • Provide a Multifaceted Approach to acid has been found to stimulate type I Bone Maintenance and Strength collagen synthesis. Type I collagen is a • Provide Foundational Support with dense, heavily cross-linked protein that Choline-Stabilized Orthosilicic Acid (ch- creates an extremely high tensile strength OSA®) and contributes to bone strength and • Support Bone Collagen Formation, Bone flexibility. These strong collagen strands Mineral Density, and Bone Calcium are believed to create core-post “binding Binding Sites sites” for calcium and other bone minerals. • Provide a Complementary Combination A 12-month, randomized, double-blind, of Micronutrients placebo-controlled (RDBPC) trial suggested that supplementing with ch-OSA conferred Fx4 Foundation Bone formula offers an additional benefit to a calcium/vitamin a variety of micronutrient profiles, D regimen by improving bone formation allowing for individualized nutrition markers and femoral neck T-scores. support of bone health and maintenance. The foundation of this distinctive formula Vitamin D3 Cholecalciferol (vitamin D3) is is choline-stabilized orthosilicic acid the form of vitamin D that is endogenously (ch-OSA®), a source of the mineral synthesized in skin during exposure to silicon. Silicon has been researched for sunlight. Unfortunately, several factors its role in collagen synthesis and bone can limit this production including smog, sunblock, and geographic location. mineral density (BMD). By adding other For many individuals, exogenous bone-specific nutrients to the ch-OSA supplementation may be beneficial. foundation, each Fx4 Foundation Bone Vitamin D plays a role in bone metabolism, formula is tailored to meet individual BMD, and calcium/phosphorus status; needs. 9