Resources from the ASH Trainee Council
FEATURE you weaker in the other . From what I ’ ve seen , the most passionate and successful physicians do both and can do both well . I think that patient care actually fuels the best research .
ASH and other organizations offer training programs that provide education and mentoring for young researchers , like the ASH Clinical Research Training Institute and Translational Research Training in Hematology .
What resources does the ASH Trainee Council provide to members ? The basic goal of the ASH Trainee Council is to advocate for issues that affect trainees and create a forum in which to discuss trainees ’ needs with the larger ASH community .
The Trainee Day at each ASH annual meeting is filled with a broad range of didactic lectures and small-group meetings focused on career development , mentoring , and obtaining funding . Outside of the annual meeting , the Trainee Council works to stay connected with trainees by providing career-development resources and a grant warehouse , which aggregates trainee opportunities in a userfriendly , searchable format . We also have the TrainE-News publication , which provides trainee-pertinent articles and board exam-style questions .
On a personal level , serving on the ASH Trainee Council has been a fantastic experience . The networking opportunities have allowed me to start projects with people outside of my institution , and learn about other programs throughout the nation . I encourage all trainees to get involved with ASH and be a voice for trainees by serving on our Trainee Council .
Females and Males of Reproductive Potential
Pregnancy Testing VYXEOS can cause fetal harm when administered to a pregnant woman [ see Use in Specific Populations ]. Verify the pregnancy status of females of reproductive potential prior to initiating VYXEOS .
Contraception
Females Advise females of reproductive potential to use effective contraception during treatment with VYXEOS and for at least 6 months after the last dose .
Males Advise males with female partners of reproductive potential to use effective contraception during treatment with VYXEOS and for at least 6 months after the last dose .
Infertility Based on findings of daunorubicin and cytarabine in animals , male fertility may be compromised by treatment with VYXEOS .
Pediatric Use Safety and effectiveness of VYXEOS in pediatric patients have not been established .
Geriatric Use Of the 375 patients who received VYXEOS ( daunorubicin 44 mg / m 2 and cytarabine 100 mg / m 2 ) liposome in clinical studies , 57 % were 65 years and over . No overall differences in safety were observed between these patients and younger patients , with the exception of bleeding events , which occurred more frequently in patients 65 years and older compared to younger patients ( 77 % vs . 59 %).
Renal Impairment Dosage adjustment is not required for patients with mild ( creatinine clearance [ CL CR
] 60 mL / min to 89 mL / min by Cockcroft Gault equation [ C-G ]) or moderate ( CL CR
30 mL / min to 59 mL / min ) renal impairment . VYXEOS has not been studied in patients with severe renal impairment ( CL CR
15 mL / min to 29 mL / min ) or end-stage renal disease .
Hepatic Impairment Dosage adjustment is not required for patients with a bilirubin level less than or equal to 3 mg / dL . VYXEOS has not been studied in patients with bilirubin level greater than 3 mg / dL .
PATIENT COUNSELING INFORMATION
Hemorrhage Inform patients of the risk of fatal bleeding . Advise patients of the need for periodic monitoring of blood counts and of the importance of keeping scheduled appointments for blood work and necessary transfusions . Advise patients to contact a healthcare provider for new onset fever or symptoms of infection or if they notice signs of bruising or bleeding [ see Warnings and Precautions and Adverse Reactions ].
Cardiotoxicity Advise patients to contact their healthcare provider if they develop symptoms of heart failure [ see Warnings and Precautions ].
Embryo-Fetal Toxicity VYXEOS can cause fetal harm when administered during pregnancy . Advise females of reproductive potential to use effective contraception during treatment and for 6 months following the last dose of VYXEOS and to inform their healthcare provider of a known or suspected pregnancy before and during treatment with VYXEOS [ see Warnings and Precautions and Use in Specific Populations ].
Lactation Advise patients not to breastfeed during treatment with VYXEOS and for at least 2 weeks after the last dose [ see Use in Specific Populations ].
Infertility Advise males of reproductive potential that VYXEOS may cause temporary or permanent infertility [ see Use in Specific Populations ].
Concomitant Medications Advise patients to speak with their physicians about any other medication they are currently taking [ see Drug Interactions ].
Hypersensitivity Reactions
Inform patients of the risk of hypersensitivity reactions , including anaphylaxis . Describe the symptoms of hypersensitivity reactions , including anaphylaxis , and instruct the patient to seek medical attention immediately if they experience such symptoms [ see Warnings and Precautions ]. © 2017 Jazz Pharmaceuticals VYX-0036 ( 1 ) a Rev0817
Resources from the ASH Trainee Council
Whether you are medical student , resident , or fellow , ASH provides many programs and resources to help you advance your career as a hematologist . Here ’ s a small sample !
TraineE-News Trainees and fellows who join ASH as associate members automatically receive TraineE-News in their inbox , a quarterly collection of articles written by and for trainees that is curated by the ASH Trainee Council . Topics range from finding a mentor to securing research funding . Visit hematology . org / TraineE-News to browse more articles from the TraineE-News archives .
Grants Clearinghouse This database of hematology grant opportunities is provided as a service by the ASH Trainee Council to aid trainees in their search for grant information . Users can quickly search for grants based on deadline , location , disease area , specialty , or other factors - rather than scanning multiple websites for hematologyrelated funding opportunities . Visit hematology . org / Fellows / Grants to start your search .
Career Timelines Every hematologist trainee , whether MD , DO , or PhD , should have a plan for career success . To help you get started , the ASH Trainee Council has created a general career-development timeline for your training . Visit hematology . org / Career / Timelines to view timelines for residency , private practice , and more .
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