ASH Clinical News September 2016 | Page 67

BACK of the BOOK Heard in the Blogosphere ASH @ASH_hematology Huge thank you to @RepBillFoster for visiting #GenomeEditing16 to better understand the challenges in the field! Alok Khorana, MD @aakonc May your p values turn >0.05 but only after reviewer 2 asked you to adjust for multiple testing. #AcademicCurses Charles Ornstein @CharlesOrnstein New word: “anecdata” Definition: A number of anecdotes when, taken together, are considered data. Goran Matijasevic, PhD @goranm To turn Healthcare System into Learning System, it will take patients to say “count me in” and share data. We Won’t Cure Cancer “Cancer isn’t space travel. The growing cancer epidemic is not a problem that medical science is about to solve. In fact, it is a problem we are about to make worse. The better we get at keeping people alive, the older they will get, and the more cancer there will be in the population. … [Our elected officials] should be mindful that, although cancer research is producing astonishing science, many more lives can be saved by doing the boring stuff, like getting people to stop smoking, eat healthfully, exercise, and put on sunscreen. And they need to prepare policies that deal with a future where more, not fewer, people have cancer. It’s not as inspiring a task as promising the moon, but it will do a lot more good.” —Jarle Breivik, MD, PhD, EdD, professor of medicine at the Institute of Basic Medical Sciences at the University of Oslo, on the misguided Cancer Moonshot in The New York Times Digitizing You and Me “Right now, we do willy-nilly testing and we have profound waste: very high false positive rates for mammograms and [prostate cancer] tests and on and on. It’s part of one-size-fits-all medicine. We’re going to develop a whole new body of medicine that is much more intelligent. I consider precision medicine digitizing you and me: Getting extraordinary, deep, rich data about each person so you can come up with better prevention, screening, and treatment. … We have too many treatments out there today that have marginal efficacy that are being applied widely. We need to develop treatments that are far more likely to succeed in a smaller swath of people.” —Eric Topol, MD, from Scripps Translational Science Institute, on adopting new technology for precision medicine in Stat News Navneet Majhail, MD @BldCancerDoc #whenonservice strength of AM coffee is inversely proportional to time taken to finish rounds. Eve Crane, MD, PhD @evemariecrane When Stopping Cancer Treatment Isn’t Giving Up New research showed that, during their last month alive, three out of four cancer patients younger than 65 received too-aggressive treatment. A much smaller portion received comfort-based hospice care instead. Caregivers and palliative-care physicians discuss the decision of when to stop aggressive cancer treatment with NBC News. “It was a whole new way of thinking to wrap our minds around. No more ‘fight mode.’ We finally felt like we were allowed to live. … I was able to be his wife versus being the one pushing all the meds. I was only given two more months with him, but I would say they were some of the best months I had with him.” —Amanda Evans-Clark, a woman whose husband died of colon cancer at the age of 31, after she and her husband decided to stop treatment Follow ASH and ASH Clinical News on: @ASH_Hematology, @BloodJournal, and @ASHClinicalNews Facebook.com/AmericanSocietyofHematology “There’s nearly nothing harder than being faced with a patient who’s begging you not to give up on them.” —Monica Malec, MD, palliative-care specialist at the University of Chicago “There are hundreds, if not thousands, who undergo too much therapy and too much suffering for every one person that we have who ends up having a miracle. When you’re dealing with young people, in their 40s, 50s, even 60s, it’s just so difficult to accept that this person is going to die.” —Otis Brawley, MD, chief medical officer of the American Cancer Society @ASH_Hematology ASHClinicalNews.org ASH Clinical News 65